Relationship between the Concentrations of Heavy Metals and Bioelements in Aging Men with Metabolic Syndrome
Bibliographic Data
| ID | 15466514 |
|---|---|
| Authors | Iwona Rotter (0000-0002-4337-6476, Pomeranian Medical University), Danuta Kosik-Bogacka (0000-0002-3796-5493, Pomeranian Medical University, corresponding author), Barbara Dołęgowska (0000-0003-3138-1013, Poznan University of Medical Sciences), Krzysztof Safranow (0000-0001-9415-2758, Pomeranian Medical University), Anna Lubkowska (0000-0002-5378-5409, Pomeranian Medical University), Maria Laszczyńska (0000-0002-1580-1885, Pomeranian Medical University) |
| Year | 2015 |
| Volume | 12 |
| Issue | 4 |
| Pages | 3944-3961 |
| Publication date | 2015-04-10 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph120403944 |
| PMID | 25867198 |
| PMCID | PMC4410226 |
| OpenAlex | W1998697859 |
| Language | EN |
| Citations received | 2 |
| References cited | 56 |
Heavy metals may exacerbate metabolic syndrome (MS) but abnormal serum concentrations of bioelements may also co-exist with MS. The primary aim of the study was to assess the relationship of blood heavy metal and bioelement concentrations and MS, in men aged 50-75 years. Heavy metals-lead (Pb), cadmium (Cd), mercury (Hg), arsenic (As), tungsten (W), Macroelements-magnesium (Mg) and calcium (Ca), and microelements-iron (Fe), zinc (Zn) copper (Cu), chromium (Cr), molybdenum (Mo), selenium (Se) and manganese (Mn), body mass index (BMI), waist to hip ratio (WHR), abdominal circumference (AC) and blood pressure (BP), total cholesterol (TCh), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG), fasting plasma glucose (FPG), insulin, and Homeostasis Model Assessment-Insulin resistance (HOMA-IR). The men with MS showed statistically significant higher Zn and lower Mg concentrations. Those with diabetes had higher Ca concentration and lower Mg concentration. Cr and Mn concentrations were significantly higher in obese men. The participants with hypertension had lower Mg concentration. We found statistically significant positive correlations (W-TCh, W-LDL, Mg-TCh, Mg-LDL, Ca-TCh, Ca-LDL, Ca-insulin, Ca-HOMAR-IR, Zn-TG, Zn-insulin, Zn-HOMA-IR, Cu-BP systolic, Mn-BMI, Mn-AC, Mn-WHR, Mn-insulin, Mn-HOMA-IR, Se-TCh, Se-LDL, Se-TG, Se-insulin, Se-HOMA-IR, Cr-TCh, Cr-HDL, Cr-LDL, Cr-TG) and negative correlations (Cd-insulin, Hg-WHR, W-insulin, W-HOMA-IR, Mg-BMI, Mg-AC, Mg-WHR, Mg-BP systolic, Mo-insulin, Mn-HDL). Tungsten may contribute to lipid disorders. Magnesium appears to play the protective role in the occurrence of metabolic disorders. Microelements Mn, Cr and Se may intensify MS
Cholesterol · Insulin · Insulin resistance · Triglyceride · Chemistry · Heavy Metal Exposure and Toxicity · Heavy metals in environment · Magnesium in Health and Disease · Medicine · Endocrinology · Internal Medicine
| Unique citing works | 2 |
|---|---|
| Citations per year | 0,33 |
| Citation span | 2020 - 2024 (5) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 2 |