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Endoscopic Endonasal Repair of Congenital Choanal Atresia

Predictive Factors of Surgical Stability and Healing Outcomes

Bibliographic Data

ID15466683
AuthorsS Ferlito (0000-0001-7136-9698, University of Catania), Antonino Maniaci (0000-0002-1251-0185, University of Catania, corresponding author), Alberto Giulio Dragonetti (Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda), Salvatore Cocuzza (0000-0002-6135-0958, University of Catania), Jérôme R Lechien (0000-0002-0845-0845, Université Paris-Saclay), Christian Calvo‐Henríquez (0000-0003-3580-0967, Rhinology Study Group of the Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), 75009 Paris, France), Juan M Solano (0000-0002-3588-9095, Hospital Universitario Virgen Macarena), Luca Giovanni Locatello (0000-0002-1879-5580, Ospedale Sant Antonio), Sebastiano Caruso (University of Catania), Francesco Nocera (0000-0001-5673-5418, University of Catania), Andrea Achena (0000-0003-1674-7179, Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda), Niccolò Mevio (0000-0002-2982-2476, Rhinology Study Group of the Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), 75009 Paris, France), Gabriella Mantini (Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda), Giorgio Luigi Ormellese (Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda), Giorgio Ormellese (Otolaryngology Unit, 9338 Ospedale Niguarda “Ca’ Granda”, 20162 Milano, Italy), Angelo Placentino (Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda), Ignazio La Mantia (0000-0002-7155-273X, University of Catania)
Year2022
Volume19
Issue15
Pages9084-9084
Publication date2022-07-26
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19159084
PMID35897454
OpenAlexW4288040641
LanguageEN
References cited32

Background: To assess the long-term outcomes and independent predictors of surgical success of a one-stage minimally invasive surgical procedure for congenital choanal atresia (C.C.A.). Methods: a retrospective multicentric study was conducted between 2010 and 2022. An endonasal endoscopic approach was performed in 38 unilateral or bilateral C.C.A. children. All the patients were clinically and radiologically assessed and followed for at least 2 years. Seven outcome measures were applied. Consequently, surgical success was correlated with all the independent variables reported. Results: 18/38 (47.36%) patients presented normal postoperative healing, 8/38 (21.05) had moderate restenosis ( 50%), requiring a surgical revision. No statistical significance was found for average hospital stay between stenosis >50% and <50% patients (p = 0.802) and postoperative pain (p = 0.075); instead, the severe restenosis group demonstrated a higher delay of breast suction (p < 0.001). Among the independent variables predictors of surgical success, the presence of Charge syndrome and rhinopharyngeal stenosis demonstrated higher risks for surgical revision (OR: 4.00, 95% CI: 0.57−28.01, and OR: 2.75, 95% CI: 0.55−13.69, respectively). On the contrary, the hypoplastic inferior turbinate and bilateral C.C.A. showed a lower risk for severe restenosis by a higher endoscopic surgical space and creating a single larger opening (OR: 0.88, 95% CI: 0.22−3.52, and OR: 0.45, 95% CI: 0.10−2.08). Conclusion: Several independent variables could influence the surgical success after C.C.A. endoscopic repair; however, more high-quality evidence is needed to generate an effective predictive model

Atresia · Choanal atresia · Restenosis · Retrospective cohort study · Stenosis · Stent · Congenital Ear and Nasal Anomalies · Ear Surgery and Otitis Media · Head and Neck Surgical Oncology · Medicine · Internal Medicine · Surgery

  • The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement

    Open Access•Erik Von Elm, David G Altman et al.•PLoS Medicine•2007

  • The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement

    Open Access•Erik Von Elm, David G Altman et al.•International Journal of Surgery•2014

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