Investigating the Joint Effect of Allostatic Load among Lesbian, Gay, and Bisexual Adults with Risk of Cancer Mortality
Bibliographic Data
| ID | 15467978 |
|---|---|
| Authors | Justin X Moore (0000-0002-5496-752X, Augusta University, corresponding author), Sydney Elizabeth Andrzejak (0000-0003-2252-9151, Augusta University Health), Sydney Andrzejak (Augusta University), Tracy Casanova (0009-0009-8891-6809, Augusta University Health), Marvin E Langston (0000-0002-4777-2425, Stanford University), Søren Estvold (Augusta University), Prajakta Adsul (0000-0003-2860-4378, University of New Mexico) |
| Year | 2023 |
| Volume | 20 |
| Issue | 12 |
| Pages | 6120-6120 |
| Publication date | 2023-06-13 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph20126120 |
| OpenAlex | W4380681170 |
| Language | EN |
| References cited | 46 |
Sexual minorities (SM) have higher chronic physiologic stress as indicated by allostatic load (AL), which may be explained in part by consistent experiences of discriminatory practices. This is one of the first studies to examine the joint effects of SM status and AL on the association with long-term risk for cancer death. Retrospective analyses were conducted on 12,470 participants using National Health and Nutrition Examination Survey (NHANES) from years 2001 through 2010 linked with the National Death Index through December 31, 2019. Cox proportional hazards models estimated adjusted hazard ratios (aHRs) of cancer deaths between groups of SM (those reporting as gay, lesbian, bisexual, or having same-sex sexual partners) status and AL. SM adults living with high AL (n = 326) had a 2-fold increased risk of cancer death (aHR: 2.55, 95% CI: 1.40–4.65) when compared to straight/heterosexual adults living with low AL (n = 6674). Among those living with high AL, SM (n = 326) had a 2-fold increased risk of cancer death (aHR: 2.26, 95% CI: 1.33–3.84) when compared to straight/heterosexual adults with high AL (n = 4957). SM with high AL have an increased risk of cancer mortality. These findings highlight important implications for promoting a focused agenda on cancer prevention with strategies that reduce chronic stress for SM adults
Allostatic load · Cancer · Confidence interval · Environmental health · Hazard ratio · Lesbian · National Death Index · National Health and Nutrition Examination Survey · Population · Proportional hazards model · Young adult · Demography · LGBTQ Health, Identity, and Policy · Medicine · Psychology · Gerontology · Internal Medicine
Price of Adaptation—Allostatic Load and Its Health Consequences
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Allostatic load biomarkers of chronic stress and impact on health and cognition
The impact of minority stress on mental health and substance use among sexual minority women.
Proportional hazards tests and diagnostics based on weighted residuals
A Proportional Hazards Model for the Subdistribution of a Competing Risk
Bridging Research and Practice
Protective and Damaging Effects of Mediators of Stress
Predictors of Anal High-Risk HPV Infection Across Time in a Cohort of Young Adult Sexual Minority Men and Transgender Women in New York City, 2015–2020
Chronic Physiologic Effects of Stress Among Lesbian, Gay, and Bisexual Adults
Racism as a stressor for African Americans
John Henryism and the health of African-Americans
Utilization of LGBT-Specific clinics and providers across three cohorts of lesbian, gay, and bisexual people in the United States
Exploring racial disparities on the association between allostatic load and cancer mortality
Origin and use of the 100 cigarette criterion in tobacco surveys
High-Effort Coping and Cardiovascular Disease among Women
Differences in Health Care Access, Utilization, and Experiences Among LGBTQ+ Subgroups in the Southern United States
Weathering” and Age Patterns of Allostatic Load Scores Among Blacks and Whites in the United States
Effectiveness-implementation Hybrid Designs
Variation in the Calculation of Allostatic Load Score
Social and psychological well-being in lesbians, gay men, and bisexuals
Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations
Minority Stress and Mental Health in Gay Men
| Citation velocity | historical |
|---|---|
| Highly cited | No |