Characteristics of Women with Lung Adenocarcinoma in the World Trade Center Environmental Health Center
Bibliographic Data
| ID | 15468172 |
|---|---|
| Authors | Elaine Shum (0000-0002-0390-5716, NYU Langone Health), Nedim Durmuş (0000-0002-4862-6497, New York City Health and Hospitals Corporation), Sultan Pehlivan (0000-0003-2848-7773, New York City Health and Hospitals Corporation), Yuting Lu (0000-0001-7632-2928, New York City Health and Hospitals Corporation), Yian Zhang (0000-0003-1974-5822, New York City Health and Hospitals Corporation), Alan A Arslan (0000-0002-7775-8085, New York City Health and Hospitals Corporation), Yongzhao Shao (0000-0003-0641-6755, New York City Health and Hospitals Corporation), Joan Reibman (0000-0001-7878-1511, New York City Health and Hospitals Corporation, corresponding author) |
| Year | 2022 |
| Volume | 19 |
| Issue | 13 |
| Pages | 7618-7618 |
| Publication date | 2022-06-22 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph19137618 |
| PMID | 35805276 |
| OpenAlex | W4283312838 |
| Language | EN |
| Citations received | 2 |
| References cited | 35 |
The destruction of the World Trade Center towers on 11 September 2001 exposed local residents, workers, and individuals in the area (Survivors) to dust and fumes that included known and suspected carcinogens. Given the potential for inhalation of toxic substances and the long latency after exposure, the incidence of lung cancer is expected to increase in WTC-exposed individuals. We describe the characteristics of women WTC Survivors with lung adenocarcinoma who were enrolled in the WTC Environmental Health Center (WTC EHC) between May 2002 and July 2021. A total of 173 women in WTC EHC had a diagnosis of any type of lung cancer, representing 10% of all cancers in women. Most of the lung cancers (87%) were non-small cell carcinomas, with adenocarcinoma (77%) being the most common subtype. Nearly half (46%) of these patients were exposed to dust clouds on 11 September 2001. Race and ethnicity varied by smoking status, as follows: 44% of Asian women compared with 29% of non-Hispanic White women were never-smokers (p < 0.001). There was no significant difference between the pathologic characteristics of adenocarcinomas between never and ever smokers. We also summarize EGFR, ALK, KRAS, ROS-1 and BRAF mutation status stratified by smoking, race and ethnicity. The identification of a relatively high proportion of women never-smokers with lung cancer warrants further investigation into the role of WTC dust exposure
Adenocarcinoma · Archaeology · Cancer · Center (category theory · Environmental health · Geography · World trade center · Injury Epidemiology and Prevention · Medicine · Occupational and environmental lung diseases · Occupational Health and Performance · Internal Medicine
Cancer statistics, 2018
Lung Cancer Characteristics in the World Trade Center Environmental Health Center
The Development of a WTC Environmental Health Center Pan-Cancer Database
Increased Incidence of Thyroid Cancer among World Trade Center First Responders
Characteristics of Cancer Patients in the World Trade Center Environmental Health Center
| Unique citing works | 2 |
|---|---|
| Citations per year | 0.5 |
| Citation span | 2022 - 2024 (3) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 2 |