High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania—Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test

Datos Bibliográficos

ID15468565
AutoresLouise Groth Grunnet (0000-0003-2298-2597, University of Copenhagen, autor de correspondencia), Line Hjort (0000-0003-4673-4176, Rigshospitalet), Daniel T R Minja (0000-0001-6159-4664, National Institute for Medical Research), Omari Abdul Msemo (0000-0002-7728-0149, National Institute for Medical Research), Sofie Lykke Møller (University of Copenhagen), Rashmi B Prasad (0000-0002-4400-6741, Lund University), Leif Groop (0000-0002-0187-3263, Lund University), John Lusingu (0000-0002-9407-0602, National Institute for Medical Research), Birgitte Nielsen (0000-0002-1715-6269, Aarhus University Hospital), Birgitte Bruun Nielsen (Aarhus University Hospital), Christentze Schmiegelow (University of Copenhagen), Ib Christian Bygbjerg (0000-0001-9100-2754, University of Copenhagen), Dirk Lund Christensen (0000-0003-2142-522X, University of Copenhagen)
Año2020
Volumen17
Número9
Páginas3109-3109
Fecha de publicación2020-04-29
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores de la revistaISSN: 1661-7827 • E-ISSN: 1660-4601
EditorialMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17093109
PMID32365670
OpenAlexW3021577319
IdiomaEN
Citas recibidas2
Referencias citadas34

Gestational diabetes mellitus (GDM) is associated with poor pregnancy outcomes and increased long-term risk of metabolic diseases for both mother and child. In Tanzania, GDM prevalence increased from 0% in 1991 to 19.5% in 2016. Anaemia has been proposed to precipitate the pathogenesis of GDM. We aimed to examine the prevalence of GDM in a rural area of Tanzania with a high prevalence of anaemia and to examine a potential association between haemoglobin concentration and blood glucose during pregnancy. The participants were included in a population-based preconception, pregnancy and birth cohort study. In total, 538 women were followed during pregnancy and scheduled for an oral glucose tolerance test (OGTT) at week 32-34 of gestation. Gestational diabetes mellitus was diagnosed according to the WHO 2013 guidelines. Out of 392 women screened, 39% (95% CI: 34.2-44.1) had GDM, the majority of whom (94.1%) were diagnosed based solely on the fasting blood sample from the OGTT. No associations were observed between haemoglobin or ferritin and glucose measurements during pregnancy. A very high prevalence of GDM was found in rural Tanzania. In view of the laborious, costly and inconvenient OGTT, alternative methods such as fasting blood glucose should be considered when screening for GDM in low- and middle-income countries

Diabetes mellitus · Environmental health · Gestation · Gestational diabetes · Glucose tolerance test · Insulin resistance · Obstetrics · Population · Pregnancy · Tanzania · Gestational Diabetes Research and Management · Iron Metabolism and Disorders · Medicine · Pregnancy and preeclampsia studies · Endocrinology