Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer
A Retrospective Analysis of Data Collected before the Lacc Trial
Bibliographic Data
| ID | 15468865 |
|---|---|
| Authors | Basilio Pecorino (0000-0001-6987-4193, Ospedale Cannizzaro), Maria Gabriella D’Agate (0000-0002-1366-0249, Ospedale Cannizzaro), Giuseppe Scibilia (0000-0002-1618-5391, Ospedale San Paolo), Paolo Scollo (0000-0001-6275-7488, Ospedale Cannizzaro), Andrea Giannini (0000-0002-4388-0082, Sapienza University of Rome), Mariano Catello Di Donna (Azienda di Rilievo Nazionale ed Alta Specializzazione), Vito Chiàntera (0000-0002-6294-3720, Azienda di Rilievo Nazionale ed Alta Specializzazione), Antonio Simone Laganà (0000-0003-1543-2802, Azienda di Rilievo Nazionale ed Alta Specializzazione, corresponding author) |
| Year | 2022 |
| Volume | 19 |
| Issue | 20 |
| Pages | 13176-13176 |
| Publication date | 2022-10-13 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph192013176 |
| PMID | 36293758 |
| OpenAlex | W4306152123 |
| Language | EN |
| Citations received | 2 |
| References cited | 28 |
Although a surgical approach is one of the key treatments for stages IA1-IIA2, results of the Laparoscopic Approach to Cervical Cancer (LACC) published in 2018 radically changed the field, since minimally invasive surgery was associated with a four-fold higher rate of recurrence and a six-fold higher rate of all-cause death compared to an open approach. We aimed to evaluate surgical outcomes of abdominal radical hysterectomy (ARH) and total laparoscopic radical hysterectomy (TLRH) for cervical cancer, including data collected before the LACC trial. In our retrospective analysis, operative time was significantly longer in TLRH compared to ARH ( p p p = 0.0874) and post-operative complication rates ( p = 0.0727) between ARH and TLRH. This was not likely to be influenced by age and Body Mass Index, since they were comparable in the two groups ( p = 0.0798 and p = 0.4825, respectively). Finally, mean number of pelvic lymph nodes retrieved ( p = 0.153) and nodal metastases ( p = 0.774), as well as death rate ( p = 0.5514) and recurrence rate ( p = 0.1582) were comparable between the two groups. Future studies should be aimed at assessing whether different histology/grades of cervical cancer, as well as particular subpopulations, may have significantly different outcomes using minimally invasive surgery or laparotomy, with or without neoadjuvant chemotherapy
Abdominal surgery · Blood loss · Cancer · Cervical cancer · Hysterectomy · Laparoscopy · Laparotomy · Mortality rate · Radical Hysterectomy · Retrospective cohort study · Endometrial and Cervical Cancer Treatments · Medicine · Ovarian cancer diagnosis and treatment · Uterine Myomas and Treatments · Internal Medicine · Surgery
| Citations per year | 0.67 |
|---|---|
| Citation span | 2023 - 2023 (1) |
| Highly cited | No |