Spatiotemporal Analysis of the Population Risk of Congenital Microcephaly in Pernambuco State, Brazil
Bibliographic Data
| ID | 15468934 |
|---|---|
| Authors | Neal Alexander (0000-0003-2455-8191, London School of Hygiene & Tropical Medicine, corresponding author), Wayner Vieira De Souza (0000-0002-0939-9332, Fundação Oswaldo Cruz), Laura Cunha Rodrigues (0000-0001-9008-660X, London School of Hygiene & Tropical Medicine), Maria Cynthia Braga (0000-0002-7862-6455, Fundação Oswaldo Cruz), Anna Luisa Silva De Oliveira (0000-0002-2483-550X, Fundação Oswaldo Cruz), Luciana Caroline Albuquerque Bezerra (0000-0001-6074-6072), Celina Maria Turchi Martelli (0000-0002-2491-0688, Fundação Oswaldo Cruz) |
| Year | 2020 |
| Volume | 17 |
| Issue | 3 |
| Pages | 700-700 |
| Publication date | 2020-01-21 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17030700 |
| PMID | 31973162 |
| OpenAlex | W3001781466 |
| Language | EN |
| References cited | 4 |
Since an outbreak in Brazil, which started in 2015, Zika has been recognized as an important cause of microcephaly. The highest burden of this outbreak was in northeast Brazil, including the state of Pernambuco. The prevalence of congenital microcephaly in Pernambuco state was estimated from the RESP (Registro de Eventos em Saúde Pública) surveillance system, from August 2015 to August 2016 inclusive. The denominators were estimated at the municipality level from official demographic data. Microcephaly was defined as a neonatal head circumference below the 3rd percentile of the Intergrowth standards. Smoothed maps of the prevalence of microcephaly were obtained from a Bayesian model which was conditional autoregressive (CAR) in space, and first order autoregressive in time. A total of 742 cases were identified. Additionally, high and early occurrences were identified in the Recife Metropolitan Region, on the coast, and in a north-south band about 300 km inland. Over a substantial part of the state, the overall prevalence, aggregating over the study period, was above 0.5%. The reasons for the high occurrence in the inland area remain unclear
Census · Environmental health · Geography · Microcephaly · Outbreak · Percentile · Population · Socioeconomics · Statistics · Zika virus · Demography · Global Maternal and Child Health · Mathematics · Medicine · Mosquito-borne diseases and control · Vibrio bacteria research studies · Pediatrics
The REporting of studies Conducted using Observational Routinely-collected health Data (Record) Statement
International standards for newborn weight, length, and head circumference by gestational age and sex
Microcephaly epidemic related to the Zika virus and living conditions in Recife, Northeast Brazil
Initial Description of the Presumed Congenital Zika Syndrome
| Highly cited | No |
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