Achievements and Challenges in the Prevention of Mother-to-Child Transmission of HIV—A Retrospective Cohort Study from a Rural Hospital in Northern Tanzania
Bibliographic Data
| ID | 15469030 |
|---|---|
| Authors | Sunniva Marie Nydal (0000-0003-0134-414X, University of Oslo), Yuda Munyaw (Haydom Lutheran Hospital), Johan N Bruun (University of Oslo), Arne Broch Brantsæter (0000-0003-1723-0577, Oslo University Hospital, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 5 |
| Pages | 2751-2751 |
| Publication date | 2021-03-09 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18052751 |
| PMID | 33803114 |
| OpenAlex | W3134530567 |
| Language | EN |
| References cited | 25 |
Despite the goal of eliminating new human immunodeficiency virus (HIV) infections in children, mother-to-child transmission is still common in resource-poor countries. The aims of this study were to assess the occurrence of mother-to-child transmission of HIV (MTCT) by age 18 months, risk factors for transmission, and the implementation of the national prevention of MTCT (PMTCT) program in a rural hospital in Tanzania. Data were collated from various medical registers and records. We included 172 children and 167 HIV-infected mothers. Among 88 children (51%) with adequate information, 9 (10.2%) were infected. Increased risk of MTCT was associated with late testing of the child (>2 months) [OR = 9.5 (95% CI: 1.8-49.4)], absence of antiretroviral therapy during pregnancy [OR = 9.7 (95% CI: 2.1-46.1)], and maternal CD4 cell count 3 [OR = 15.3 (95% CI: 2.1-111)]. We were unable to determine the occurrence of MTCT transmission in 84 children (49%). The results from this study highlight that there is an urgent need for enhanced efforts to improve follow-up of HIV-exposed children, to improve documentation in registries and records, and to facilitate ease of linkage between these
Cohort · Cohort study · Environmental health · Family medicine · Geography · Human immunodeficiency virus (HIV · Medical record · Population · Pregnancy · Record linkage · Retrospective cohort study · Tanzania · Transmission (telecommunications · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Internal Medicine · Pediatrics · Surgery
Prevention of Mother-to-Child HIV Transmission in Resource-Poor Countries
Challenges with routine data sources for PMTCT programme monitoring in East Africa
Early infant diagnosis of HIV in three regions in Tanzania; successes and challenges
Reducing mother-to-child transmission of HIV
Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at a PMTCT clinic in northwest Ethiopia
Outcomes of prevention of mother to child transmission of the human immunodeficiency virus-1 in rural Kenya—a cohort study
| Highly cited | No |
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