Cost-Effectiveness Analysis from a Randomized Controlled Trial of Tailored Exercise Prescription for Women with Breast Cancer with 8-Year Follow-Up
Bibliographic Data
| ID | 15469688 |
|---|---|
| Authors | Louisa G Gordon (0000-0002-3159-4249, Queensland University of Technology, corresponding author), Elizabeth Eakin (0000-0002-8835-9995, The University of Queensland), Elizabeth G Eakin (The University of Queensland), Rosalind R Spence (0000-0002-5446-5562, Griffith University), Christopher Pyke (0000-0002-8764-0742, Mater Private Hospital), John Bashford (Wesley Hospital), Christobel Saunders (0000-0003-2281-9829, The University of Western Australia), Sandra C Hayes (0000-0002-7005-5184, Griffith University) |
| Year | 2020 |
| Volume | 17 |
| Issue | 22 |
| Pages | 8608-8608 |
| Publication date | 2020-11-19 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17228608 |
| PMID | 33228174 |
| OpenAlex | W3109511009 |
| Language | EN |
| Citations received | 1 |
| References cited | 35 |
Studies show conflicting results on whether exercise interventions to improve outcomes for women with breast cancer are cost-effective. We modelled the long-term cost-effectiveness of the Exercise for Health intervention compared with usual care. A lifetime Markov cohort model for women with early breast cancer was constructed taking a societal perspective. Data were obtained from trial, epidemiological, quality of life, and healthcare cost reports. Outcomes were calculated from 5000 Monte Carlo simulations, and one-way and probabilistic sensitivity analyses. Over the cohort's remaining life, the incremental cost for the exercise versus usual care groups were $7409 and quality-adjusted life years (QALYs) gained were 0.35 resulting in an incremental cost per QALY ratio of AU$21,247 (95% Uncertainty Interval (UI): Dominant, AU$31,398). The likelihood that the exercise intervention was cost-effective at acceptable levels was 93.0%. The incremental cost per life year gained was AU$8894 (95% UI Dominant, AU$11,769) with a 99.4% probability of being cost effective. Findings were most sensitive to the probability of recurrence in the exercise and usual care groups, followed by the costs of out-of-pocket expenses and the model starting age. This exercise intervention for women after early-stage breast cancer is cost-effective and would be a sound investment of healthcare resources
Breast cancer · Cancer · Cohort · Confidence interval · Cost effectiveness · Cost–benefit analysis · Health care · Incremental cost-effectiveness ratio · Physical therapy · Psychological intervention · Quality of life (healthcare · Quality-adjusted life year · Randomized controlled trial · Risk analysis (engineering · Breast Cancer Treatment Studies · Cancer survivorship and care · Health Systems, Economic Evaluations, Quality of Life · Medicine · Nursing · Internal Medicine · Surgery
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,33 |
| Citation span | 2023 - 2023 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |