Respiratory Effects of Fine and Ultrafine Particles from Indoor Sources—A Randomized Sham-Controlled Exposure Study of Healthy Volunteers

Bibliographic Data

ID15470673
AuthorsVanessa Soppa (Leibniz Institute of Environmental Medicine, corresponding author), Roel P F Schins (0000-0001-5881-6289, Leibniz Institute of Environmental Medicine), Roel Schins (IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany), Frauke Hennig (0000-0002-8769-7976, Leibniz Institute of Environmental Medicine), Bryan Hellack (0000-0003-2398-982X, Institut für Energie- und Umwelttechnik), Ulrich Quaß (Institut für Energie- und Umwelttechnik), Heinz Kaminski (Institut für Energie- und Umwelttechnik), Thomas A J Kuhlbusch (0000-0001-7847-9304, Institut für Energie- und Umwelttechnik), Thomas Kuhlbusch (Air Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58–60, 47229 Duisburg, Germany), Barbara Hoffmann (0000-0002-8435-5575, Heinrich Heine University Düsseldorf), Gudrun Weinmayr (Leibniz Institute of Environmental Medicine)
Year2014
Volume11
Issue7
Pages6871-6889
Publication date2014-07-04
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph110706871
PMID25000149
PMCIDPMC4113851
OpenAlexW1993514965
LanguageEN
Citations received4
References cited32

Particulate air pollution is linked to impaired respiratory health. We analyzed particle emissions from common indoor sources (candles burning (CB), toasting bread (TB), frying sausages (FS)) and lung function in 55 healthy volunteers (mean age 33.0 years) in a randomized cross-over controlled exposure study. Lung-deposited particle surface area concentration (PSC), size-specific particle number concentration (PNC) up to 10 μm, and particle mass concentration (PMC) of PM1, PM2.5 and PM10 were determined during exposure (2 h). FEV1, FVC and MEF25%–75% was measured before, 4 h and 24 h after exposure. Wilcoxon-rank sum tests (comparing exposure scenarios) and mixed linear regression using particle concentrations and adjusting for personal characteristics, travel time and transportation means before exposure sessions were performed. While no effect was seen comparing the exposure scenarios and in the unadjusted model, inverse associations were found for PMC from CB and FS in relation to FEV1 and MEF25%–75%. with a change in 10 μg/m3 in PM2.5 from CB being associated with a change in FEV1 of −19 mL (95%-confidence interval:−43; 5) after 4 h. PMC from TB and PNC of UFP were not associated with lung function changes, but PSC from CB was. Elevated indoor fine particles from certain sources may be associated with small decreases in lung function in healthy adults

Anesthesia · Animal science · Biology · Confidence interval · Inhalation · Inhalation exposure · Linear regression · Lung · Lung function · Particulates · Respiratory system · Statistics · Ultrafine particle · Air Quality and Health Impacts · Chemistry · Climate Change and Health Impacts · Mathematics · Medicine · Noise Effects and Management · Internal Medicine · Toxicology

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