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Associations of Cognitive Complaints and Depressive Symptoms with Health-Related Quality of Life and Perceived Overall Health in Japanese Adult Volunteers

Bibliographic Data

ID15470770
AuthorsKuniyoshi Toyoshima (0000-0002-5618-3657, Hokkaido University, corresponding author), Takeshi Inoue (0000-0003-3289-4478, Tokyo Medical University), Toshiaki Baba (0000-0003-0146-7027, National Center for Global Health and Medicine), Jiro Masuya (0000-0003-1220-9592, Tokyo Medical University), Masahiko Ichiki (Tokyo Medical University), Yota Fujimura (0000-0001-5961-7249, Tokyo Medical University), Ichiro Kusumi (0000-0002-8747-5070, Hokkaido University)
Year2021
Volume18
Issue18
Pages9647-9647
Publication date2021-09-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18189647
PMID34574573
OpenAlexW3200024868
LanguageEN
References cited15

Cognitive complaints, defined as perceived cognitive dysfunction in daily living, are associated with depressive symptoms. The associations of cognitive complaints and depressive symptoms with health-related quality of life (HRQoL) and perceived overall health in Japanese adults remains unknown. To investigate these relationships, we evaluated a convenience sample of 525 Japanese adult volunteers (Mage: 41.3 ± 11.7; 238 male and 287 female). We used the Cognitive Complaints in Bipolar Disorder Rating Assessment (evaluating cognitive complaints), Patient Health Questionnaire-9 (evaluating depressive symptoms), EuroQol-5 Dimension-5 Level (EQ-5D-5L; evaluating HRQoL), and EuroQol-Visual Analogue Scale (EQ-VAS; evaluating perceived overall health). Our path analyses suggested that both cognitive complaints and depressive symptoms had significant total effects on HRQoL and perceived overall health. Furthermore, cognitive complaints were not significantly associated directly with HRQoL and perceived overall health, whereas cognitive complaints were significantly associated with HRQoL and perceived overall health indirectly via depressive symptoms. Depressive symptoms were significantly associated directly with HRQoL and perceived overall health. This study suggests that depressive symptoms may mediate the associations of cognitive complaints with HRQoL and perceived overall health. Thus, to address the HRQoL and perceived overall health associated with cognitive complaints, evaluation and intervention for depressive symptoms may be useful in public health

Cognition · Depression (economics · Depressive symptoms · Psychiatry · Quality of life (healthcare · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Clinical Psychology · Dementia and Cognitive Impairment Research · Medicine · Schizophrenia research and treatment

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