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Mild to Severe Neurological Manifestations of Covid-19

Cases Reports

Bibliographic Data

ID15470835
AuthorsGabriele Melegari (0000-0003-4512-4835, Azienda Ospedaliero-Universitaria di Modena, corresponding author), Veronica Rivi (0000-0002-8413-4510, University of Modena and Reggio Emilia), Gabriele Zelent (Azienda Ospedaliero-Universitaria di Modena), Vincenzo Nasillo (0000-0001-5122-5574, Azienda Unita' Sanitaria Locale Di Modena), Elena De Santis (0000-0001-6415-6969, Azienda Unita' Sanitaria Locale Di Modena), Alessandra Melegari (Azienda Unita' Sanitaria Locale Di Modena), Claudia Bevilacqua (0000-0003-0423-4624, University of Modena and Reggio Emilia), Michele Zoli (0000-0002-8034-2849, University of Modena and Reggio Emilia), Stefano Meletti (0000-0003-0334-539X, Azienda Ospedaliero-Universitaria di Modena), Alberto Barbieri (0000-0002-0733-0008, University of Modena and Reggio Emilia)
Year2021
Volume18
Issue7
Pages3673-3673
Publication date2021-04-01
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18073673
PMID33915937
OpenAlexW3147583493
LanguageEN
References cited60

The main focus of Coronavirus disease 2019 (COVID-19) infection is pulmonary complications through virus-related neurological manifestations, ranging from mild to severe, such as encephalitis, cerebral thrombosis, neurocognitive (dementia-like) syndrome, and delirium. The hospital screening procedures for quickly recognizing neurological manifestations of COVID-19 are often complicated by other coexisting symptoms and can be obscured by the deep sedation procedures required for critically ill patients. Here, we present two different case-reports of COVID-19 patients, describing neurological complications, diagnostic imaging such as olfactory bulb damage (a mild and unclear underestimated complication) and a severe and sudden thrombotic stroke complicated with hemorrhage with a low-level cytokine storm and respiratory symptom resolution. We discuss the possible mechanisms of virus entrance, together with the causes of COVID-19-related encephalitis, olfactory bulb damage, ischemic stroke, and intracranial hemorrhage

Anesthesia · Complication · Coronavirus disease 2019 (COVID-19 · Cytokine storm · Delirium · Dementia · Disease · Encephalitis · Intensive care medicine · Intracerebral hemorrhage · Stroke (engine · Subarachnoid hemorrhage · Thrombosis · Venous thrombosis · Virus · COVID-19 Clinical Research Studies · Infectious Encephalopathies and Encephalitis · Long-Term Effects of COVID-19 · Medicine · Immunology · Internal Medicine · Pediatrics

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Highly citedNo

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