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Relationship between Bell’s Palsy and Previous Statin Use

A Case/Non-Case Study

Bibliographic Data

ID15472990
AuthorsSo Young Kim (0000-0003-2258-7490, CHA University Bundang Medical Center), Jee Hye Wee (0000-0002-6513-7011, Hallym University), Chanyang Min (0000-0002-0629-9299, Seoul National University), Dae Myoung Yoo (0000-0003-2511-5536, Hallym University), Hyo Geun Choi (0000-0003-1655-9549, Hallym University, corresponding author)
Year2020
Volume17
Issue22
Pages8408-8408
Publication date2020-11-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17228408
PMID33202921
OpenAlexW3100564956
LanguageEN
Citations received2
References cited2

We intended to determine the relationship between previous statin use and Bell's palsy in a large study population receiving statins for the past 2 years. The Korean National Health Insurance Service-Health Screening Cohort data from 2002 to 2015 were collected. Participants with Bell's palsy ( n = 3203) were matched with participants without Bell's palsy ( n = 12,812). The number of days of previous statin use for 2 years before the onset of Bell's palsy was analyzed using conditional logistic regression. Subgroups of age, sex, obesity, smoking, alcohol consumption, total cholesterol, and blood pressure were analyzed for any association between Bell's palsy and prior statin use. The Bell's palsy group reported greater statin use than the non-Bell's palsy group (84.6 (standard deviation, SD = 201.7) vs. 74.4(SD = 189.4), p = 0.009). Previous statin use was associated with Bell's palsy in the crude model (95% confidence intervals = 1.03-1.19, p = 0.006). However, this relationship disappeared when the possible covariates were adjusted for in model 2. All subgroups showed no increased odds for Bell's palsy in previous statin users. We did not find an association between Bell's palsy and previous statin use in this Korean population aged ≥40 years

Bell Palsy · Bell's palsy · Cohort · Cohort study · Confidence interval · Environmental health · Logistic regression · Odds ratio · Palsy · Physical therapy · Population · Statin · Facial Nerve Paralysis Treatment and Research · Medicine · Orthopedic Surgery and Rehabilitation · Internal Medicine · Pediatrics

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Unique citing works2
Citations per year0.4
Citation span2021 - 2021 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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