Comparison of Mean Platelet Counts in Preterm Infants with and without Retinopathy of Prematurity
Bibliographic Data
| ID | 15475124 |
|---|---|
| Authors | Zi Di Lim (Universiti Sains Malaysia), Edwin Pheng (Universiti Sains Malaysia), Evelyn Li Min Tai (0000-0001-8055-5396, Universiti Sains Malaysia, corresponding author), Hans Van Rostenberghe (0000-0002-7908-8994, Universiti Sains Malaysia), Ismail Shatriah (0000-0002-4753-4814, Universiti Sains Malaysia, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 7 |
| Pages | 3783-3783 |
| Publication date | 2021-04-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18073783 |
| PMID | 33916368 |
| OpenAlex | W3141470400 |
| Language | EN |
| Citations received | 1 |
| References cited | 41 |
Platelets are a primary source of pro- and anti-angiogenic cytokines. However, the evidence of their role in retinopathy of prematurity (ROP) is controversial. This retrospective study aimed to compare mean weekly platelet counts between infants with and without ROP over the first 6 weeks of life. A total of 93 infants matched by gestational age and birth weight were recruited (31 with ROP, 62 without ROP). Weekly mean platelet counts and other related risk factors were documented. The repeated measure analysis of variance (ANOVA) and the repeated measure analysis of covariance (ANCOVA) were used to compare mean platelet counts over time between the two groups, with and without adjusting for confounders. We found significant differences in the weekly mean platelet counts of infants with and without ROP over the first 6 weeks of life ( p = 0.002). These differences disappeared after adjusting for covariates ( p = 0.489). Lower mean platelet counts in ROP infants are not directly related to ROP, but rather to the presence of other risk factors for ROP, such as culture-proven sepsis, blood transfusion and bronchopulmonary dysplasia
Analysis of variance · Birth weight · Bronchopulmonary dysplasia · Confounding · Gestational age · Neonatal intensive care unit · Neonatal sepsis · Platelet · Pregnancy · Repeated measures design · Retinopathy of prematurity · Sepsis · Medicine · Neonatal Health and Biochemistry · Neonatal Respiratory Health Research · Retinopathy of Prematurity Studies · Internal Medicine · Pediatrics
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,33 |
| Citation span | 2023 - 2023 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |