Influence of the Menstrual Cycle on Blood Markers of Muscle Damage and Inflammation Following Eccentric Exercise
Bibliographic Data
The aim of this study was to evaluate whether the menstrual cycle and its underlying hormonal fluctuations affect muscle damage and inflammation in well-trained females following an eccentric exercise. Nineteen eumenorrheic women performed an eccentric squat-based exercise in the early follicular phase, late follicular phase and mid-luteal phase of their menstrual cycle. Sex hormones and blood markers of muscle damage and inflammation -creatine kinase, myoglobin, lactate dehydrogenase, interleukin-6, tumoral necrosis factor-, and C reactive protein- were analyzed in each phase. No effect of menstrual cycle phase was observed ( p > 0.05), while an interaction for interleukin-6 was shown ( p = 0.047). Accordingly, a moderate effect size [0.68 (0.53)-0.84 (0.74)], indicated that interleukin-6 values 2 h post-trial (2.07 1.26 pg/mL) were likely to be higher than baseline (1.59 0.33 pg/mL), 24 h (1.50 0.01 pg/mL) and 48 h (1.54 0.13 pg/mL) in the mid-luteal phase. Blood markers of muscle damage and inflammation were not affected by the menstrual cycle in well-trained women. The eccentric exercise barely triggered muscle damage and hence, no inflammation was observed, possibly due to participants training status. The mid-luteal phase was the only phase reflecting a possible inflammatory response in terms of interleukin-6, although further factors than sex hormones seem to be responsible for this finding
Acute-phase protein · Creatine kinase · Eccentric · Follicular phase · Hormone · Inflammation · Luteal phase · Menstrual cycle · Exercise and Physiological Responses · Medicine · Muscle metabolism and nutrition · Sports injuries and prevention · Endocrinology · Internal Medicine
Biomarkers of exercise-induced muscle damage and inflammation across menstrual cycle phases
Efectos de la fase menstrual en el rendimiento y bienestar de mujeres jóvenes futbolistas (Effects of the menstrual phase on the performance and well-being of female young soccer players)
Considerations for Sex-Cognizant Research in Exercise Biology and Medicine
Influence of Menstrual Cycle on Leukocyte Response Following Exercise-Induced Muscle Damage
Menstrual Cycle Phases Influence on Cardiorespiratory Response to Exercise in Endurance-Trained Females
Capillary Blood Recovery Variables in Young Swimmers
Basal Values of Biochemical and Hematological Parameters in Elite Athletes
Stigma, menstrual etiquette, and identity work
| Citations per year | 1.6 |
|---|---|
| Citation span | 2021 - 2026 (6) |
| Highly cited | No |