Serum Lipid Profile and Its Association with Diabetes and Prediabetes in a Rural Bangladeshi Population

Bibliographic Data

ID15475740
AuthorsBishwajit Bhowmik (0000-0003-1114-5873, University of Oslo, corresponding author), Tasnima Siddiquee (Centre for Global Health Research), Anindita Mujumder (Dhaka Medical College and Hospital), Faria Afsana (0000-0002-7412-2196, Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders), Tareen Ahmed (Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders), Ibrahimu Mdala (0000-0002-5204-1934, University of Oslo), Ibrahimu A Mdala (University of Oslo), Nayla Cristina do Vale Moreira (0000-0001-5585-4271, University of Oslo), Abul Kalam Azad Khan (Centre for Global Health Research), Akhtar Hussain (0000-0003-4870-3365, Nord University), Gerd Holmboe-Ottesen (University of Oslo), Gerd Holmboe‐Ottesen (University of Oslo), Tone Kristin Omsland (0000-0002-0808-3133, University of Oslo)
Year2018
Volume15
Issue9
Pages1944-1944
Publication date2018-09-06
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph15091944
PMID30200612
OpenAlexW2890699547
LanguageEN
Citations received5
References cited49

Dyslipidemia is commonly associated with diabetes (T2DM). This has been demonstrated for the Caucasian population, but few data are available for Asian Indians. The paper aims to investigate serum lipids (separately or in combination) and their association with glucose intolerance status (T2DM and prediabetes) in a rural Bangladeshi population. A sample of 2293 adults (≥20 years) were included in a community based cross-sectional survey in 2009. Anthropometric measures, blood pressure, blood glucose (fasting and 2-h oral glucose tolerance test) and fasting serum lipids (total cholesterol, T-Chol; triglycerides, Tg; low density lipoprotein cholesterol, LDL-C and high density lipoprotein cholesterol, HDL-C) were registered. Analysis of covariance (ANCOVA) and regression analysis were performed. High Tg levels were seen in 26% to 64% of the participants, depending on glucose tolerance status. Low HDL-C levels were seen in all groups (>90%). Significant linear trends were observed for high T-Chol, high Tg and low HDL-C with increasing glucose intolerance ( p for trend p p p = 0.044). Prediabetes showed a significant association with high Tg (OR: 1.96, p p = 0.011). Participants with combined high Tg and low HDL-C levels had a 12.75-fold higher OR for T2DM and 4.89 OR for prediabetes. In Asian Indian populations an assessment of serum lipids is warranted not only for T2DM patients, but also for those with prediabetes

Anthropometry · Cholesterol · Diabetes mellitus · Dyslipidemia · Environmental health · Glucose tolerance test · High-density lipoprotein · Impaired fasting glucose · Impaired glucose tolerance · Insulin resistance · Population · Prediabetes · Type 2 diabetes · Diabetes, Cardiovascular Risks, and Lipoproteins · Lipid metabolism and disorders · Liver Disease Diagnosis and Treatment · Medicine · Endocrinology · Internal Medicine

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