Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes

A Pilot Study

Bibliographic Data

ID15475786
AuthorsGiorgio Orlando (0000-0001-6721-8248, Manchester Metropolitan University, corresponding author), Jamie K Pugh (Loughborough University), Jamie Pugh (University of Birmingham), Steve H Faulkner (0000-0003-4688-7252, Loughborough University), Stefano Balducci (0000-0001-8128-3863, Azienda Ospedaliera Sant'Andrea), Massimo Sacchetti (0000-0002-5365-5161, Foro Italico University of Rome), Giuseppe Pugliese (0000-0003-1574-0397, Azienda Ospedaliera Sant'Andrea), Ilenia Bazzucchi (0000-0002-6017-1683, Foro Italico University of Rome), Jonida Haxhi (0000-0003-2319-869X, Azienda Ospedaliera Sant'Andrea), Eduardo Martinez‐Valdes (0000-0002-5790-7514, University of Birmingham), Eduardo Martinez-Valdes (University of Birmingham), Deborah Falla (0000-0003-1689-6190, University of Birmingham), Konstantinos Manolopoulos (0000-0001-8890-6090, University of Birmingham), Myra A Nimmo (0000-0003-1045-5167, Loughborough University)
Year2023
Volume20
Issue18
Pages6746-6746
Publication date2023-09-12
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph20186746
PMID37754606
OpenAlexW4386629305
LanguageEN
Citations received1
References cited27

This pilot study aimed to compare the effects of eight weeks of concurrent resistance training (RT) and high-intensity interval training (HIIT) vs. RT alone on muscle performance, mass and quality in adults with type 2 diabetes (T2DM). Twelve T2DM adults were randomly allocated to the RT + HIIT (n = 5) or RT (n = 7) group. Before and after training, maximal oxygen uptake (VO 2max ), muscle strength and power were evaluated by calorimetry, dynamometry and one-repetition maximum (1RM) test. Quadriceps muscle volume was determined by MRI, and muscle quality was estimated. After RT, VO 2max (+12%), knee muscle power (+20%), quadriceps muscle volume (+5.9%) and quality (leg extension, +65.4%; leg step-up, +223%) and 1RM at leg extension (+66.4%), leg step-up (+267%), lat pulldown (+60.9%) and chest press (+61.2%) significantly increased. The RT + HIIT group improved on VO 2max (+27%), muscle volume (+6%), muscle power (+9%) and 1RM at lat pulldown (+47%). No other differences were detected. Among groups, changes in muscle quality at leg step-up and leg extension and VO 2max were significantly different. The combination of RT and HIIT effectively improves muscle function and size and increases cardiorespiratory fitness in adults with T2DM. However, HIIT combined with RT may interfere with the development of muscle quality

Blood pressure · Cardiology · Cardiorespiratory fitness · Heart rate · High-intensity interval training · Interval training · Leg press · Physical medicine and rehabilitation · Physical therapy · Resistance training · VO2 max · Cardiovascular and exercise physiology · Medicine · Muscle metabolism and nutrition · Physical Activity and Health · Internal Medicine

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