Occurrence of Idiopathic Pulmonary Fibrosis in Italy
Latest Evidence from Real-World Data
Bibliographic Data
The aim of the study was to evaluate the trend in the incidence of idiopathic pulmonary fibrosis (IPF) in a real-world setting of the Marche region, a region of Central Italy, between 2014 and 2019. This observational prospective study was based on administrative databases of hospital discharges and drug prescriptions. All adult residents in the Marche Region with a first prescription of antifibrotic drugs, or a first hospitalization with a diagnosis of IPF during the study period, were identified as incident cases of IPF. A multiple Poisson regression analysis was used to estimate the IPF incidence trend, adjusted for age, sex, and health conditions. The mean incidence rate was 9.8 cases per 100,000 person-years. A significant increasing trend of 6% per year was observed. The incidence rates were significantly higher in males than females, older subjects, and those with poorer health conditions. To our knowledge, this is the first study evaluating incidences of IPF over a 6-year period in Italy, combining hospital discharge and drug prescription databases. The study highlights that the combined use of two secondary sources is a reliable strategy to accurately identify new cases of IPF when the appropriate disease registry is lacking
Environmental health · Idiopathic pulmonary fibrosis · Incidence (geometry · Lung · Medical prescription · Observational study · Poisson regression · Population · Prospective cohort study · Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis · Medicine · Occupational and environmental lung diseases · Sarcoidosis and Beryllium Toxicity Research · Emergency Medicine · Epidemiology · Internal Medicine
| Citations per year | 0.25 |
|---|---|
| Citation span | 2022 - 2022 (1) |
| Highly cited | No |