Effects of Resistance Training Combined with Vitamin D Supplementation on Health-Related Variables in the Elderly

Muscle Strength, Body Composition, and Inflammatory Status

Bibliographic Data

ID15475839
AuthorsLorena Rosa (0000-0002-8323-0113, Universidade do Estado do Rio de Janeiro), Lorena Cristina Ribeiro da Rosa (Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracanã Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil), Paulo De Tarso Veras Farinatti (0000-0003-2463-1280, Universidade do Estado do Rio de Janeiro), Maria Izabel Ferreira Batista (0000-0003-3134-4271, Universidade do Estado do Rio de Janeiro), Hilene Ribeiro Santiago Navarro Machado (0000-0002-9319-5411, Universidade do Estado do Rio de Janeiro, corresponding author), Victor Hugo Fonseca de Jesus (0000-0003-4702-116X, Universidade do Estado do Rio de Janeiro), Vitor Hugo Silva de Jesus (Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracanã Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil), Weslen do Nascimento Dantas (Universidade do Estado do Rio de Janeiro), Patrícia Maria Lourenço Dutra (0000-0002-2494-6912, Universidade do Estado do Rio de Janeiro), Nádia Souza Lima Da Silva (0000-0003-0617-0521, Universidade do Estado do Rio de Janeiro)
Year2025
Volume22
Issue11
Pages1695-1695
Publication date2025-11-10
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph22111695
PMID41302641
OpenAlexW4416093299
LanguageEN
References cited30

Aging is associated with changes in body composition that lead to low-grade chronic inflammation, compromising the health of the elderly. This condition can be mitigated by resistance training (RT) and vitamin D supplementation, promoting the health of this population. This study aimed to investigate the effects of 12 weeks of RT combined with vitamin D supplementation on body composition, muscle strength, and inflammatory status in older adults. A total of 26 participants were randomly assigned to an Experimental Group (EG: n = 12; 11 Female; 70.6 ± 4.7 years; RT + 2000 IU/day of vitamin D) and a Control Group (EG: n = 14; 11 Female; 69.6 ± 4.6 years; RT + placebo). Both groups performed the same RT program (8 exercises; 2 sets; 10 RM, twice per week). Before and after the intervention, participants were assessed using DEXA, strength tests (sit-to-stand test and handgrip strength), and serum biomarkers (IL-6, TNF-α, 25(OH)D). Both groups showed significant strength gains, particularly in the lower limbs ( p p > 0.05 for all tests and groups). A time × group interaction was observed for IL-6 ( p = 0.03), with a slight reduction in the EG and an increase in the CG, although post-intervention differences were not statistically significant ( p = 0.49). No statistically significant between-group difference in 25(OH)D change ( p = 0.11). These findings suggest that vitamin D supplementation at the tested dose did not enhance adaptations to resistance training in older adults with normal baseline vitamin D levels. Further studies are warranted to explore potential benefits in deficient populations and with alternative dosing strategies

Inflammation · Muscle strength · Resistance training · Vitamin · Vitamin D and neurology · vitamin D deficiency · Cardiovascular and exercise physiology · Exercise and Physiological Responses · Vitamin D Research Studies

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