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Residential Proximity to Major Roadways and Risk of Type 2 Diabetes Mellitus

A Meta-Analysis

Bibliographic Data

ID15477811
AuthorsZhiqing Zhao (0000-0003-4215-2486, Tangshan People's Hospital), Faying Lin (The Eighth Hospital of Xi'an), Bennett Wang (Affiliated Hospital of Qingdao University), Yihai Cao (0000-0003-1308-0065, Karolinska Institutet), Xu Hou (0000-0002-2781-7219, Qingdao University, corresponding author), Yangang Wang (0000-0003-1298-9963, Qingdao University, corresponding author)
Year2016
Volume14
Issue1
Pages3-3
Publication date2016-12-22
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph14010003
PMID28025522
OpenAlexW2561805914
LanguageEN
Citations received3
References cited11

Research indicates that higher levels of traffic-related pollution exposure increase the risk of diabetes, but the association between road proximity and diabetes risk remains unclear. To assess and quantify the association between residential proximity to major roadways and type 2 diabetes, a systematic review and meta-analysis was performed. Embase, Medline, and Web of Science were searched for eligible studies. Using a random-effects meta-analysis, the summary relative risks (RRs) were calculated. Bayesian meta-analysis was also performed. Eight studies (6 cohort and 2 cross-sectional) with 158,576 participants were finally included. The summary unadjusted RR for type 2 diabetes associated with residential proximity to major roadways was 1.24 (95% confidence interval [CI]: 1.07-1.44, p = 0.001, I2 = 48.1%). The summary adjusted RR of type 2 diabetes associated with residential proximity to major roadways was 1.12 (95% CI: 1.03-1.22, p = 0.01, I2 = 17.9%). After excluding two cross-sectional studies, the summary results suggested that residential proximity to major roadways could increase type 2 diabetes risk (Adjusted RR = 1.13; 95% CI: 1.02-1.27, p = 0.025, I2 = 36.6%). Bayesian meta-analysis showed that the unadjusted RR and adjusted RR of type 2 diabetes associated with residential proximity to major roadways were 1.22 (95% credibility interval: 1.06-1.55) and 1.13 (95% credibility interval: 1.01-1.31), respectively. The meta-analysis suggested that residential proximity to major roadways could significantly increase risk of type 2 diabetes, and it is an independent risk factor of type 2 diabetes. More well-designed studies are needed to further strengthen the evidence

Diabetes mellitus · Environmental health · Meta-analysis · Poison control · Type 2 diabetes · Type 2 Diabetes Mellitus · Human Factors and Ergonomics · Medicine · Urban Transport and Accessibility · Endocrinology · Internal Medicine

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Citations per year0.5
Citation span2020 - 2020 (1)
Highly citedNo

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