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Maternal and Neonatal Levels of Perfluoroalkyl Substances in Relation to Gestational Weight Gain

Dados Bibliográficos

ID15478317
AutoresJillian Ashley‐Martin (0000-0001-9958-7531, Izaak Walton Killam Health Centre), Linda Dodds (0000-0002-7463-0166, Dalhousie University, autor correspondente), Tye E Arbuckle (Health Canada), Anne-Sophie Morisset (0000-0002-9214-8912, Université de Montréal), Mandy Fisher (0000-0003-4656-3813, Health Canada), Maryse F Bouchard (0000-0001-6246-4802, Université de Montréal), Gabriel D Shapiro (0000-0002-3139-0238, McGill University), Adrienne S Ettinger (0000-0002-0200-8677, University of Michigan), Patricia Monnier (0000-0001-9839-8149, McGill University), Renée Dallaire (Université Laval), Shayne Taback (University of Manitoba), William D Fraser (0000-0001-9042-2415, Université de Sherbrooke)
Ano2016
Volume13
Fascículo1
Páginas146-146
Data de publicação2016-01-20
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores do periódicoISSN: 1661-7827 • E-ISSN: 1660-4601
EditoraMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph13010146
PMID26805861
OpenAlexW2286768909
IdiomaEN
Citações recebidas4
Referências citadas1

Perfluoroalkyl substances (PFASs) are ubiquitous, persistent pollutants widely used in the production of common household and consumer goods. There is a limited body of literature suggesting that these chemicals may alter metabolic pathways and growth trajectories. The relationship between prenatal exposures to these chemicals and gestational weight gain (GWG) has received limited attention. One objective was to analyze the associations among maternal plasma levels of three common perfluoroalkyl substances (perfluorooctanoate (PFOA), perfluorooctanesulfonate (PFOS), perfluorohexanesulfanoate (PFHxS)) and GWG. Additionally, we explored whether GWG was associated with cord blood PFAS levels. This study utilized data collected in the Maternal-Infant Research on Environmental Chemicals (MIREC) Study, a trans-Canada cohort study of 2001 pregnant women. Our analysis quantified associations between (1) maternal PFAS concentrations and GWG and (2) GWG and cord blood PFAS concentrations. Maternal PFOS concentrations were positively associated with GWG (β = 0.39 95% CI: 0.02, 0.75). Interquartile increases in GWG were significantly associated with elevated cord blood PFOA (OR = 1.33; 95% CI: 1.13 to 1.56) and PFOS (OR = 1.20; 95% CI: 1.03 to 1.40) concentrations. No statistically significant associations were observed between GWG and either measure of PFHxS. These findings warrant elucidation of the potential underlying mechanisms

Biology · Body weight · Cord blood · Environmental health · Fetus · Gestation · Obstetrics · Pregnancy · Weight gain · Air Quality and Health Impacts · Medicine · Per- and polyfluoroalkyl substances research · Toxic Organic Pollutants Impact · Endocrinology · Internal Medicine · Physiology

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  • Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China

    Open Access•Gehui Wang, Jianjiang Lu et al.•International Journal of…•2017

  • Occurrence of Perfluorooctanoic Acid and Perfluorooctane Sulfonate in Milk and Yogurt and Their Risk Assessment

    Open Access•Zhenni Xing, Jianjiang Lu et al.•International Journal of…•2016

  • Anthropometric Characteristics of Young Adults in Areas With Different Ecological Risks in the Aral Sea Region, Uzbekistan

    Open Access•O Yerkudov, V O Yerkudov et al.•Ekologiya Cheloveka (Human Ecology•2020

  • The Web of Risk Factors for Excessive Gestational Weight Gain in Low Income Women

    Open Access•Keriann H Paul, Meredith L Graham et al.•Maternal and Child Health Journal•2012

Obras citantes distintas4
Citações por ano0,4
Intervalo de citações2016 - 2020 (5)
Velocidade de citaçãohistorical
Altamente citadoNão
Tipos de citaçãoNeutras: 4
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