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Gender Differences in Depression and Quality of Life in Current and Abstinent Ketamine Users

Bibliographic Data

ID15480290
AuthorsPeng‐Wei Wang (0000-0002-6224-8920, Kaohsiung Medical University, corresponding author), Peng-Wei Wang (Kaohsiung Medical University), Cheng-Fang Yen (0000-0003-1156-4939, Kaohsiung Medical University), Hung‐Chi Wu (0000-0001-5627-9969, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital), Chih‐Yao Hsu (0000-0002-7692-3106, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital), Chih-Yao Hsu (Departments of Addiction Science, Kai-Suan Psychiatric Hospital, Kaohsiung 80708, Taiwan), Yu-Yi Yang (Kaohsiung Medical University)
Year2021
Volume18
Issue18
Pages9567-9567
Publication date2021-09-10
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18189567
PMID34574490
OpenAlexW3201589602
LanguageEN
Citations received1
References cited42

Ketamine use has become of increasing concern because it has spread in many parts of the world during the past few years. Substance users usually have depression and a lower quality of life (QoL). The aim of this study was to explore depression and QoL in ketamine users, and to further examine the role of gender in relation to differences in depression and QoL in ketamine users. This study recruited 204 current ketamine users, 102 abstinent ketamine users and 102 healthy controls. The demographic data, severity of depression and QoL were recorded. Analysis of Variance (ANOVA) was employed to compare the associations of ketamine use status with depression and QoL. Gender differences were examined by moderator analysis. The current ketamine users with and without ketamine use disorder, in addition to the abstinent ketamine users with ketamine use disorder, have more severe depression and a lower QoL than healthy controls. There were significant gender differences in depression and QoL in abstinent ketamine users with ketamine use disorder. Ketamine users have more severe depression and a lower QoL. In particular, depression and a lower QoL are still prominent in abstinent ketamine users. The gender differences in depression and QoL are significant in abstinent ketamine users

Depression (economics · Ketamine · Moderation · Psychiatry · Psychotherapist · Quality of life (healthcare · Clinical Psychology · Medicine · Mental Health Research Topics · Psychology · Treatment of Major Depression · Tryptophan and brain disorders

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Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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