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Radiation Exposure Predicts Reported Vaccine Adverse Effects in Veterans with Gulf War Illness

Bibliographic Data

ID15480380
AuthorsBeatrice A Golomb (0000-0002-4454-0485, University of California San Diego, corresponding author), Emily Nguyen (0009-0005-3696-6872, University of California San Diego), Eero Dinkeloo (University of California San Diego)
Year2020
Volume17
Issue19
Pages7136-7136
Publication date2020-09-29
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17197136
PMID33003502
OpenAlexW3091281236
LanguageEN
Citations received2
References cited74

Most people have no problems when administered vaccines; however, as with all drugs, reported adverse effects (rAEs) do occur. There is a need to better understand the potential predictors of reported vaccine AEs (rVaxAEs), including modifiable (environmental) predictors. Gulf War Veterans (GWV) who have Gulf War illness (GWI) report increased experiences of drug and chemical rAEs, extending to rVaxAEs. GWV provide an opportunity to examine the relationship between their reported exposures and rAEs. Forty one GWV with GWI and 40 healthy controls reported exposure and rAEs to exposure, including for 14 vaccines. Individual and summed vaccine exposures, rVaxAEs, and reported Vaccine AE Propensity (summed rVaxAEs/summed vaccines exposures) were compared in cases vs. controls. Exposure-outcome assessments focused on GWV, using a multivariable regression with robust standard error. More designated vaccines were reported in cases than in controls: 9.0 (2.3) vs. 3.8 (2.3), p p < 0.0001. Multivariable assessment confirmed that radiation and pesticides remained significant statistical predictors of reported Vaccine AE Propensity. Exposure tied to excess rVaxAEs in GWV may contribute to, or underlie, the reported link between rVaxAEs in GWV and later ill health

Adverse effect · Environmental health · Geography · Gulf war · Heat illness · Psychiatry · Climate Change and Health Impacts · Fibromyalgia and Chronic Fatigue Syndrome Research · History · Medicine · Spaceflight effects on biology · Internal Medicine

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Citations per year2
Citation span2026 - 2026 (1)
Highly citedNo

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