Analyses of Commercially Available Alcohol-Based Hand Rubs Formulated with Compliant and Non-Compliant Ethanol
Bibliographic Data
| ID | 15480410 |
|---|---|
| Authors | Timothy J Tse (0000-0002-6359-0736, University of Saskatchewan, corresponding author), Fina B Nelson (0000-0001-6589-3469, University of Saskatchewan), Martin J T Reaney (Jinan University, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 7 |
| Pages | 3766-3766 |
| Publication date | 2021-04-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18073766 |
| PMID | 33916568 |
| OpenAlex | W3148632171 |
| Language | EN |
| Citations received | 2 |
| References cited | 35 |
The COVID-19 pandemic led to panic-buying of alcohol-based hand rubs (ABHRs). In response, governmental agencies (e.g., Health Canada) permitted the sale of ABHRs formulated with "technical-grade" ethanol to alleviate the growing demand. Technical-grade ethanol contains elevated concentrations of impurities (e.g., acetaldehyde, etc.), which may exhibit dose-dependent toxicity. In this study, a rapid solvent extraction was employed to analyze gelled ABHRs via gas chromatography with flame ionization detection. In total, 26 liquid and 16 gelled ABHRs were analyzed for nine common impurities to determine compliance with Health Canada interim guidelines. Of 42 samples analyzed, 11 ABHRs appear to be non-compliant with interim Health Canada guidelines. Non-compliant ABHRs exhibited elevated concentrations of acetaldehyde, with a maximal concentration observed of 251 ± 10 μL L -1 ; 3.3× higher than currently permitted. Nonetheless, frequent testing of ABHRs should be routinely conducted to reduce the risk of consumer exposure to non-compliant ABHRs
Acetaldehyde · Alcohol · Chromatography · Ethanol · Solvent · Chemistry · Food Safety and Hygiene · Infection Control and Ventilation · Infection Control in Healthcare · Organic Chemistry
| Citations per year | 0.5 |
|---|---|
| Citation span | 2022 - 2025 (4) |
| Highly cited | No |