Effect of Obstructive Sleep Apnea and CPAP Treatment on the Bioavailability of Erythrocyte and Plasma Nitric Oxide

Bibliographic Data

ID15480622
AuthorsJ Mochol (0000-0001-5731-5271, Wroclaw Medical University, corresponding author), Jakub Gawryś (0000-0003-4520-3496, Wroclaw Medical University), Ewa Szahidewicz-Krupska (0000-0002-4446-6991, Wroclaw Medical University), Jerzy Wiśniewski (0000-0003-2831-7643, Wrocław University of Science and Technology), Paulina Fortuna (0000-0003-4617-798X, Wroclaw Medical University), Piotr Rola (0000-0002-0963-2712, Wroclaw Medical University), Helena Martynowicz (0000-0003-1283-8460, Wroclaw Medical University), Adrian Doroszko (0000-0001-5472-028X, Wroclaw Medical University)
Year2022
Volume19
Issue22
Pages14719-14719
Publication date2022-11-09
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph192214719
PMID36429438
OpenAlexW4308869728
LanguageEN
References cited43

The erythrocyte pool of the NO metabolic pathway intermediates does not depend on OSA and its treatment, whereas the erythrocytes could constitute a high-volume buffer in their storage Hence, the results from this prospective study are a step forward in understanding the role of the erythrocyte compartment and the intra-erythrocyte pathways regulating NO bioavailability and paracrine endothelial function in the hypoxia-reoxygenation setting, such as obstructive sleep apnea

Arginine · Asymmetric dimethylarginine · Bioavailability · Citrulline · Continuous positive airway pressure · Endothelial Dysfunction · Nitric oxide · Nitric oxide synthase · Obstructive sleep apnea · Cardiovascular and Diving-Related Complications · Chemistry · Medicine · Neuroscience of respiration and sleep · Obstructive Sleep Apnea Research · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

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