The Blood Lead Levels of Children and the Loss of Ca2+ from Neurons Owing to Lead
Bibliographic Data
| ID | 15480800 |
|---|---|
| Authors | Yifei Duan (0000-0001-8443-1606, Sichuan University), Hua Shi (0000-0001-7013-1565, Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China), Shi H (0000-0002-9958-9892, Sichuan University), Yongmei Jiang (0000-0002-0487-1888, West China Second University Hospital of Sichuan University, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 22 |
| Pages | 12051-12051 |
| Publication date | 2021-11-17 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph182212051 |
| PMID | 34831808 |
| OpenAlex | W3211886110 |
| Language | EN |
| Citations received | 1 |
| References cited | 16 |
In order to understand current blood lead levels (BLLs), we investigated the BLLs of children in Sichuan Province from 2011 to 2020. We then monitored the treatment effects of calcium in children with high BLLs to assess their treatment status. Finally, we explored the effects of lead on Ca 2+ through in-situ experiments. Whole blood samples were used for BLL tests. The BLLs of 76,362 children aged 0-7 years were measured using atomic absorption spectrometry. The median BLL was 35 μg/L (interquartile range: 28-47). The BLLs were significantly higher in boys than in girls ( p 2+ levels in neurons of mice brain slices, and the effect did not subside immediately even after the lead was removed. China has made rapid progress in pediatric healthcare, but the treatment status remains unsatisfactory. Because lead causes an irreversible loss of Ca 2+ , there is an urgent need to develop new standardized treatments to reduce the treatment duration
Biology · Blood lead level · Environmental health · Interquartile range · Lead (geology · Lead exposure · Lead poisoning · Psychiatry · Heavy Metal Exposure and Toxicity · Heavy metals in environment · Medicine · Trace Elements in Health · Internal Medicine · Pediatrics
| Citations per year | 0.33 |
|---|---|
| Citation span | 2023 - 2023 (1) |
| Highly cited | No |