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An Age-Period-Cohort Analysis of Biomarkers of Lifestyle-Related Diseases Using the National Health and Nutrition Survey in Japan, 1973–2018

Bibliographic Data

ID15480804
AuthorsTasuku Okui (0000-0001-5098-8502, Kyushu University Hospital, corresponding author)
Year2020
Volume17
Issue21
Pages8159-8159
Publication date2020-11-04
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17218159
PMID33158284
OpenAlexW3096437997
LanguageEN
References cited43

Studies of biomarkers of lifestyle-related diseases in Japanese cohorts are scarce. This study aimed to analyze trends in risk markers of lifestyle-related diseases using age-period-cohort (APC) analysis. Data on systolic blood pressure and BMI from 1973 to 2018 and serum glucose, triglyceride, and high-density lipoprotein cholesterol levels from 1989 to 2018 available from the National Health and Nutrition Survey were used. Values for each of the risk markers for each age, period, and cohort were estimated using APC analysis. For women, a decrease in all the risk markers of lifestyle-related diseases was observed in individuals born between the 1930s and approximately 1970. Therefore, female individuals born in approximately 1970 were considered to have the lowest risk of developing lifestyle-related and cardiovascular diseases. Meanwhile, the cohort effect on all the risk markers deteriorated for the younger cohorts, and changes in lifestyle behavior are needed for cohorts born more recently. For men, the trends in risk markers across the cohorts differed, and the relative risk of lifestyle-related diseases for each cohort differed according to disease. These results could help understand cohort-specific risks for lifestyle-related disease and enable identification of high-risk populations who could benefit from preventive measures

Cohort · Cohort effect · Cohort study · Disease · Environmental health · National Health and Nutrition Examination Survey · Population · Birth, Development, and Health · Demography · Medicine · Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Gerontology · Internal Medicine

  • What has made the population of Japan healthy?

    Open Access•Nayu Ikeda, Eiko Saito et al.•The Lancet•2011

  • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016

    Open Access•Leandra Abarca-Gómez, Ziad Abdeen et al.•The Lancet•2017

  • Prevalence and Correlates of Hypertension among Japanese Adults, 1975 to 2010

    Open Access•Katharina Otani, Rei Haruyama et al.•International Journal of…•2018

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