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NO2 and Cancer Incidence in Saudi Arabia

Bibliographic Data

ID15480896
AuthorsKhalid Al‐Ahmadi (0000-0001-7079-8730, King Abdulaziz City for Science and Technology, corresponding author), Ali Al‐Zahrani (0000-0001-9183-6150, King Faisal Specialist Hospital & Research Centre)
Year2013
Volume10
Issue11
Pages5844-5862
Publication date2013-11-04
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph10115844
PMID24192792
PMCIDPMC3863874
OpenAlexW2079252331
LanguageEN
Citations received10
References cited17

Air pollution exposure has been shown to be associated with an increased risk of specific cancers. This study investigated whether the number and incidence of the most common cancers in Saudi Arabia were associated with urban air pollution exposure, specifically NO2. Overall, high model goodness of fit (GOF) was observed in the Eastern, Riyadh and Makkah regions. The significant coefficients of determination (r2) were higher at the regional level (r2 = 0.32-0.71), weaker at the governorate level (r2 = 0.03-0.43), and declined slightly at the city level (r2 = 0.17-0.33), suggesting that an increased aggregated spatial level increased the explained variability and the model GOF. However, the low GOF at the lowest spatial level suggests that additional variation remains unexplained. At different spatial levels, associations between NO2 concentration and the most common cancers were marginally improved in geographically weighted regression (GWR) analysis, which explained both global and local heterogeneity and variations in cancer incidence. High coefficients of determination were observed between NO2 concentration and lung and breast cancer incidences, followed by prostate, bladder, cervical and ovarian cancers, confirming results from other studies. These results could be improved using individual explanatory variables such as environmental, demographic, behavioral, socio-economic, and genetic risk factors

Breast cancer · Cancer · Cervical cancer · Environmental health · Incidence (geometry · Lung cancer · Prostate cancer · Regression analysis · Statistics · Air Quality and Health Impacts · Climate Change and Health Impacts · Demography · Mathematics · Medicine · Urban Transport and Accessibility · Internal Medicine · Oncology

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Unique citing works10
Citations per year0,77
Citation span2013 - 2025 (13)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 10

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