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Characteristics and Outcome Determinants of Hospitalized Older Patients with Cognitive Dysfunction

Bibliographic Data

ID15480924
AuthorsYi-Ting Chao (Taichung Veterans General Hospital), Fu-Hsuan Kuo (Taichung Veterans General Hospital), Yu-Shan Lee (0000-0003-1084-1113, Taichung Veterans General Hospital), Yuhui Huang (0000-0003-1985-3575, Taichung Veterans General Hospital), Yu-Hui Huang (0000-0003-3884-2695, Center for Geriatrics & Gerontology, Taichung Veterans General Hospital, Taichung 407219, Taiwan), Shuo‐Chun Weng (0000-0001-5269-1155, National Yang Ming Chiao Tung University), Yin‐Yi Chou (Taichung Veterans General Hospital), Yin-Yi Chou (Center for Geriatrics & Gerontology, Taichung Veterans General Hospital, Taichung 407219, Taiwan), Chu‐Sheng Lin (0000-0002-3502-9204, Taichung Veterans General Hospital), Chu-Sheng Lin (Center for Geriatrics & Gerontology, Taichung Veterans General Hospital, Taichung 407219, Taiwan), Shih‐Yi Lin (0000-0002-1901-2656, National Yang Ming Chiao Tung University, corresponding author)
Year2022
Volume19
Issue1
Pages584-584
Publication date2022-01-05
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19010584
PMID35010842
OpenAlexW4206550681
LanguageEN
Citations received1
References cited45

Cognitive dysfunction commonly occurs among older patients during admission and is associated with adverse prognosis. This study evaluated clinical characteristics and outcome determinants in hospitalized older patients with cognitive disorders. The main outcomes were length of stay, readmission within 30 days, Barthel index (BI) score at discharge, BI score change (discharge BI score minus BI score), and proportion of positive BI score change to indicate change of activities of daily living (ADL) change during hospitalization. A total of 642 inpatients with a mean age of 79.47 years (76-103 years) were categorized into three groups according to the medical history of dementia, and Mini-Mental State Examination (MMSE) scores at admission. Among them, 74 had dementia diagnosis (DD), 310 had cognitive impairment (CI), and 258 had normal MMSE scores. Patients with DD and CI generally had a higher risk of many geriatric syndromes, such as multimorbidities, polypharmacy, delirium, incontinence, visual and auditory impairment, fall history, physical frailty. They had less BI score, BI score change, and proportion of positive BI score change ADL at discharge. (DD 70.0%, CI 79.0%), suggesting less ADL change during hospitalization compared with those with normal MMSE scores (92.9%; p p = 0.008) and walking speed ( p = 0.023) were predictors of discharge BI score. In addition, age ( p = 0.047) and education level were associated with dichotomized BI score change (positive vs. non-positive) during hospitalization. Furthermore, the number and severity of comorbidities predicted LOS ( p p = 0.001) in patients with cognitive disorders. It is suggested that appropriate strategies are required to improve clinical outcomes in these patients

Activities of daily living · Barthel index · Cognition · Delirium · Dementia · Physical therapy · Polypharmacy · Psychiatry · Dementia and Cognitive Impairment Research · Frailty in Older Adults · Intensive Care Unit Cognitive Disorders · Medicine · Internal Medicine

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Unique citing works1
Citations per year0,25
Citation span2022 - 2022 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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