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Association between Altitude and the Framingham Risk Score

A Cross-Sectional Study in the Peruvian Adult Population

Bibliographic Data

ID15481983
AuthorsAkram Hernández-Vásquez (0000-0003-1431-2526, Universidad San Ignacio de Loyola, corresponding author), Rodrigo Vargas-Fernández (0000-0002-3310-8689, Universidad Científica del Sur), Manuel Chacón-Díaz (0000-0002-5554-7578, Instituto Nacional de Salud del Niño)
Year2022
Volume19
Issue7
Pages3838-3838
Publication date2022-03-23
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19073838
PMID35409522
OpenAlexW4220951756
LanguageEN
Citations received3
References cited43

To determine the association between altitude and the Framingham risk score in the Peruvian population, we performed a cross-sectional analytical study of data collected by the 2017-2018 Food and Nutrition Surveillance by Life Stages survey. The outcome of this study was the Framingham 10-year cardiovascular disease event risk prediction, which is composed of six modifiable and non-modifiable coronary risk factors. A generalized linear model (GLM) of the gamma family and log link function was used to report the crude and adjusted β coefficients. Several sensitivity analyses were performed to assess the association of interest. Data from a total of 833 surveyed participants were included. After adjusting for educational level, poverty level, alcohol consumption, physical activity level, the presence of any limitation, obesity, and area of residence, it was observed that altitude ≥ 2500 m above sea level (β = -0.42 [95% CI: -0.69 to -0.16]) was negatively and significantly associated with a decrease in the Framingham 10-year risk score. High altitude was significantly and negatively associated with Framingham 10-year risk scores. Our results will allow prevention strategies considering modifiable risk factors to avoid the development of cardiovascular diseases, especially in people living at low altitudes

Cross-sectional study · Disease · Environmental health · Framingham Heart Study · Framingham Risk Score · Population · Cardiovascular Health and Risk Factors · Demography · Diabetes, Cardiovascular Risks, and Lipoproteins · High Altitude and Hypoxia · Medicine · Gerontology · Internal Medicine

  • Short-term trends in hypertension and high cardiovascular risk at high altitude in Peru

    Open Access•Brando Ortiz-Saavedra, Julio S Mamani-Castillo et al.•Frontiers in Public Health•2026

  • The Association between Altitude and Waist–Height Ratio in Peruvian Adults

    Open Access•Akram Hernández-Vásquez, Diego Azañedo•International Journal of…•2022

  • Prevalence of Prehypertension and Associated Cardiovascular Risk Profiles among Adults in Peru

    Open Access•Akram Hernández-Vásquez, Rodrigo Vargas-Fernández•International Journal of…•2022

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Citations per year0.75
Citation span2022 - 2026 (5)
Highly citedNo

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