Sex-Specific Relationships of Physical Activity and Sedentary Behaviour with Oxidative Stress and Inflammatory Markers in Young Adults
Bibliographic Data
| ID | 15482177 |
|---|---|
| Authors | Juan Corral‐Pérez (0000-0002-6574-9827, Universidad de Cádiz), Martín Alcalá (0000-0003-4678-8860, Universidad San Pablo CEU), Daniel Velázquez‐Díaz (0000-0001-6270-9208, Universidad de Cádiz), Alejandro Pérez‐Bey (0000-0002-9849-5544, Universidad de Cádiz), María Ángeles Vázquez‐Sánchez (0000-0001-7785-5857, Universidad de Málaga), María Calderón‐Domínguez (0000-0003-1797-3450, Universidad de Cádiz), Cristina Casals (0000-0002-6992-0492, Universidad de Cádiz, corresponding author), Jesús Gustavo Ponce‐González (0000-0002-5982-7761, Universidad de Cádiz) |
| Year | 2023 |
| Volume | 20 |
| Issue | 2 |
| Pages | 899-899 |
| Publication date | 2023-01-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph20020899 |
| PMID | 36673654 |
| OpenAlex | W4313584614 |
| Language | EN |
| Citations received | 1 |
| References cited | 44 |
This study aims to analyse sex-specific associations of physical activity and sedentary behaviour with oxidative stress and inflammatory markers in a young-adult population. Sixty participants (21 women, 22.63 ± 4.62 years old) wore a hip accelerometer for 7 consecutive days to estimate their physical activity and sedentarism. Oxidative stress (catalase, superoxide dismutase, glutathione peroxidase, glutathione, malondialdehyde, and advanced oxidation protein products) and inflammatory (tumour necrosis factor-alpha and interleukin-6) markers were measured. Student t-tests and single linear regressions were applied. The women presented higher catalase activity and glutathione concentrations, and lower levels of advanced protein-oxidation products, tumour necrosis factor-alpha, and interleukin-6 than the men (p < 0.05). In the men, longer sedentary time was associated with lower catalase activity (β = −0.315, p = 0.04), and longer sedentary breaks and higher physical-activity expenditures were associated with malondialdehyde (β = −0.308, p = 0.04). Vigorous physical activity was related to inflammatory markers in the women (tumour necrosis factor-alpha, β = 0.437, p = 0.02) and men (interleukin−6, β = 0.528, p < 0.01). In conclusion, the women presented a better redox and inflammatory status than the men; however, oxidative-stress markers were associated with physical activity and sedentary behaviours only in the men. In light of this, women could have better protection against the deleterious effect of sedentarism but a worse adaptation to daily physical activity
Biology · Catalase · Environmental health · Enzyme · Glutathione · Glutathione peroxidase · Malondialdehyde · Oxidative stress · Physical activity · Physical therapy · Population · Superoxide dismutase · Tumor necrosis factor alpha · Cardiovascular and exercise physiology · Exercise and Physiological Responses · Medicine · Physical Activity and Health · Biochemistry · Endocrinology · Internal Medicine
Validation and comparison of ActiGraph activity monitors
Validation of Accelerometer Wear and Nonwear Time Classification Algorithm
Validation of Wearable Monitors for Assessing Sedentary Behavior
Accelerometer Data Collection and Processing Criteria to Assess Physical Activity and Other Outcomes
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
Accelerometer Use in Physical Activity
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |