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Pregnancy with Heart Disease

Maternal Outcomes and Risk Factors for Fetal Growth Restriction

Bibliographic Data

ID15482884
AuthorsNguyễn Mạnh Thắng (0000-0002-5270-7855, Hanoi Medical University), Nhon Bui Van (0000-0001-7018-1669, Hanoi Medical University, corresponding author), Huyen Le Thi (Hanoi Medical University), Hoang-Long Vo (0000-0001-5992-875X, Hanoi Medical University), Hao Nguyen Si Anh (0000-0002-3287-4808, Hanoi Medical University), Huong Trinh Thi Thu, Thuc Nguyen Xuan, Nga Vu Thi (Duy Tan University, corresponding author), Le Minh Bui (0000-0002-1283-8324, Trường ĐH Nguyễn Tất Thành, corresponding author), Dinh-Toi Chu (0000-0002-4596-2022, Hanoi National University of Education, corresponding author)
Year2019
Volume16
Issue12
Pages2075-2075
Publication date2019-06-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph16122075
PMID31212780
OpenAlexW2950836202
LanguageEN
Citations received1

Caring for children and mothers suffering from cardiac disease is highly challenging, with issues including late diagnosis as well as inadequate infrastructure and supply of drugs. We aimed to evaluate maternal outcomes among pregnant women suffering from heart disease with a live birth, and explored the risk factors for fetal growth restriction among these patients. A retrospective study was performed at the National Hospital of Obstetrics and Gynecology (Hanoi, Vietnam) over a 3-year period from 2014 to 2016. A total of 284 patients were enrolled in the study. Overall, most women were aged below 35 years and were diagnosed with heart disease before pregnancy. Of the women experiencing rheumatic heart disease, the prevalence of mitral valve regurgitation was the highest (40.14%), while the figure for aortic valve regurgitation was the lowest (4.23%). Of women with congenital heart defects, the most common defects were ventricular septal defect (VSD) and atrial septal defect (ASD) (19.37% and 16.55%, respectively), while 5.28% of mothers were diagnosed with tetralogy of Fallot and 1.76% with patent ductus arteriosus. Noted clinical presentations of the patients included palpitation (63.38%), breathlessness (23.59%), leg edema (8.45%), and chest pain (8.1%). The common complications in the study population included 16.90% of women having heart failure and 19.37% having arrhythmias. The incidence of fetal growth restriction was 9.15%. Hypertension (odds ratio (OR): 59.75, 95% confidence interval (CI): 9.1-392.17), the heart disease types (ASD (OR: 4.27, 95% CI: 1.19-15.29) and tetralogy of Fallot (OR: 6.82, 95% CI: 1.21-38.55)), and the complications (heart failure (OR: 10.34, 95% CI: 2.75-38.87) and pulmonary edema (OR: 107.16, 95% CI: 4.96-2313.93)) were observed as risk factors for intrauterine growth restriction. This study provides a cornerstone to promote further studies and to motivate people to apply evidence-based medical care for mothers with diagnosed cardiac disease in the antenatal and postnatal periods

Cardiology · Ductus arteriosus · Heart disease · Heart failure · Obstetrics · Odds ratio · Population · Pregnancy · Tetralogy of Fallot · Cardiac Structural Anomalies and Repair · Cardiovascular Issues in Pregnancy · Medicine · Pulmonary Hypertension Research and Treatments · Internal Medicine · Pediatrics

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Unique citing works1
Citations per year0.17
Citation span2020 - 2020 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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