Change in Asthma Is Associated with Change in PTSD in World Trade Center Health Registrants, 2011 to 2016
Bibliographic Data
The WTC Health Registry (WTCHR) is a closed, longitudinal cohort of rescue/recovery workers and survivors exposed to the 11 September 2001 disaster. WTCHR enrollees diagnosed with asthma after 11 September 2001 continued to experience poor control despite treatment. Asthma is associated with mental problems, although their bidirectional movement has not been studied. This study tested whether a clinical change in mental problems was associated with a difference in asthma control, and whether a change in asthma control varied with a change in quality of life (QoL). Difference in the Asthma Control Test (ACT) on the WTCHR from 2011-12 to 2015-16 was compared with the change in the Post-traumatic Stress Disorder Checklist (PCL-17), the Patient Health Questionnaire depression scale, self-reported heartburn, and change of physical and mental QoL over this period. In adjusted multinomial multivariable logistic regression, improved PCL-17 was associated with a better ACT score, odds ratio (OR) = 1.42 (95% C.I. 1.01, 1.99), and a worsened PCL-17 score was associated with a worsened ACT score, OR = 1.77 (95% C.I. 1.26, 2.50). Decreased ACT was associated with poor physical QoL, OR = 1.97 (95% C.I. 1.48, 2.62). Change in mental health measures tracked with change in asthma control, which correlated with a change in QoL. Careful follow-up and treatment of all three are indicated to improve these inter-related issues
Asthma · Checklist · Cohort · Depression (economics · Logistic regression · Mental health · Multinomial logistic regression · Odds · Odds ratio · Physical therapy · Psychiatry · Quality of life (healthcare · Medicine · Occupational Health and Performance · Posttraumatic Stress Disorder Research · Psychology · Resilience and Mental Health · Internal Medicine
Asthma and Posttraumatic Stress Symptoms 5 to 6 Years Following Exposure to the World Trade Center Terrorist Attack
Development of the asthma control test
Psychometric properties of the PTSD checklist (PCL)
Probable Posttraumatic Stress Disorder and Lower Respiratory Symptoms Among Rescue/Recovery Workers and Community Members After the 9/11 World Trade Center Attacks—A Longitudinal Mediation Analysis
An Overview of 9/11 Experiences and Respiratory and Mental Health Conditions among World Trade Center Health Registry Enrollees
Interpretation of Changes in Health-related Quality of Life
Monitoring Depression Treatment Outcomes With the Patient Health Questionnaire-9
| Citation velocity | historical |
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| Highly cited | No |