Urinary Mineral Concentrations in European Pre-Adolescent Children and Their Association with Calcaneal Bone Quantitative Ultrasound Measurements

Datos Bibliográficos

ID15486136
AutoresKaren Van den Bussche (0000-0001-5308-8729, Ghent University Hospital, autor de correspondencia), Diana Herrmann (0000-0002-1103-6274, Leibniz Institute for Prevention Research and Epidemiology - BIPS), Stefaan De Henauw (0000-0003-4141-5432, HOGENT University of Applied Sciences and Arts), Yiannis Kourides (Cyprus Institute), Fabio Lauria (0000-0002-1663-1582, Institute of Food Science), Staffan Mårild (0000-0001-6517-2020, University of Gothenburg), Dénes Molnár (0000-0002-3675-7019, University of Pecs), Luis Alberto Moreno Aznar (0000-0003-0454-653X, Universidad de Zaragoza), Toomas Veidebaum (0000-0001-7659-8924, National Institute for Health Development), Wolfgang Ahrens (0000-0003-3777-570X, University of Bremen), Isabelle Sioen (0000-0002-7139-9691, Ghent University Hospital)
Año2016
Volumen13
Número5
Páginas471-471
Fecha de publicación2016-05-05
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores de la revistaISSN: 1661-7827 • E-ISSN: 1660-4601
EditorialMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph13050471
PMID27164120
OpenAlexW2346062414
IdiomaEN
Citas recibidas1
Referencias citadas54

This study investigates differences and associations between urinary mineral concentrations and calcaneal bone measures assessed by quantitative ultrasonography (QUS) in 4322 children (3.1-11.9 years, 50.6% boys) from seven European countries. Urinary mineral concentrations and calcaneal QUS parameters differed significantly across countries. Clustering revealed a lower stiffness index (SI) in children with low and medium urinary mineral concentrations, and a higher SI in children with high urinary mineral concentrations. Urinary sodium (uNa) was positively correlated with urinary calcium (uCa), and was positively associated with broadband ultrasound attenuation and SI after adjustment for age, sex and fat-free mass. Urinary potassium (uK) was negatively correlated with uCa but positively associated with speed of sound after adjustment. No association was found between uCa and QUS parameters after adjustment, but when additionally adjusting for uNa, uCa was negatively associated with SI. Our findings suggest that urinary mineral concentrations are associated with calcaneal QUS parameters and may therefore implicate bone properties. These findings should be confirmed in longitudinal studies that include the food intake and repeated measurement of urinary mineral concentrations to better estimate usual intake and minimize bias

Bone mineral · Calcaneus · Osteoporosis · Ultrasound · Urinary calcium · Urinary system · Urine · Medicine · Nutritional Studies and Diet · Renal function and acid-base balance · Sodium Intake and Health · Endocrinology · Physiology · Surgery