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Prevalence of Oral Clefts among Live Births in Gansu Province, China

Bibliographic Data

ID15488939
AuthorsMengying Wang (0000-0002-4766-3608, Peking University), Ruogu Meng (0000-0001-8366-6147, Peking University), Zhuqing Wang (0000-0002-3988-0733, Peking University), Dongjing Liu (0000-0002-9520-7789, Peking University), Hui Huang (0000-0002-3410-556X, Peking University), Chuyun Kang (Peking University), Hongtian Li (0000-0002-9972-0838, National Bureau of Statistics of China), Tao Wu (0000-0002-0133-6783, Peking University, corresponding author), Siyan Zhan (0000-0001-7252-5349, Peking University)
Year2018
Volume15
Issue2
Pages380-380
Publication date2018-02-23
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph15020380
PMID29473843
OpenAlexW2792389585
LanguageEN
Citations received1

Background: Oral clefts (OCs) are common human birth defects. Children with OCs in underdeveloped regions are more likely to suffer from poverty and hardship in their future lives. Here, we attempted to estimate the prevalence of OCs among live births in Gansu Province in 2008 to understand the epidemiologic pattern of the disease. Methods: A cross-sectional study was conducted from January 2008 to December 2008 in Gansu Province. The live births delivered between January and December 2008 with OCs were investigated through face-to-face questionnaire survey. Results: A total of 468 infants with OCs were identified among 347,137 live births in 2008 in Gansu Province, which yielded a prevalence of 1.35 per 1000 live births. The majority of these cases were CL (cleft lip) (prevalence = 0.85 per 1000 live births), and the prevalence of CLP (cleft lip and palate) and CP (cleft palate) was 0.34 and 0.11 per 1000 live births, respectively. We also found that the prevalence of OCs in Jiayuguan (3.39 per 1000 live births) and Dingxi (2.71 per 1000 live births) was higher than those of other cities in Gansu Province. Additionally, we failed to detect significant correlation between economic conditions of the cities and the prevalence of OCs in our study. Conclusions: The prevalence of OCs among live births in Gansu Province in 2008 was higher than the prevalence of OCs in other provinces in China. The high prevalence may reflect the need for further etiological studies to explore the potential risk factors in this region. In addition, more subtype information needs to be collected in future prevalence studies for better understanding of the epidemiologic pattern of the disease

China · Cross-sectional study · Environmental health · Etiology · Geography · Live birth · Poverty · Pregnancy · Cleft Lip and Palate Research · Congenital Anomalies and Fetal Surgery · Craniofacial Disorders and Treatments · Demography · Medicine · Epidemiology

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Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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