Toxicity Assessment of Refill Liquids for Electronic Cigarettes
Bibliographic Data
| ID | 15490083 |
|---|---|
| Authors | Vincent Varlet (0000-0003-3805-4664, University Centre of Legal Medicine), Konstantinos E Farsalinos (0000-0001-6839-4710, University of Patras), Marc Augsburger (0000-0002-5606-3831, University Centre of Legal Medicine), Aurélien Thomas (0000-0001-6790-2285, University Centre of Legal Medicine), Jean-François Etter (0000-0002-1426-3157, University of Geneva, corresponding author) |
| Year | 2015 |
| Volume | 12 |
| Issue | 5 |
| Pages | 4796-4815 |
| Publication date | 2015-04-30 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph120504796 |
| PMID | 25941845 |
| PMCID | PMC4454939 |
| OpenAlex | W2145060683 |
| Language | EN |
| Citations received | 7 |
| References cited | 28 |
We analyzed 42 models from 14 brands of refill liquids for e-cigarettes for the presence of micro-organisms, diethylene glycol, ethylene glycol, hydrocarbons, ethanol, aldehydes, tobacco-specific nitrosamines, and solvents. All the liquids under scrutiny complied with norms for the absence of yeast, mold, aerobic microbes, Staphylococcus aureus, and Pseudomonas aeruginosa. Diethylene glycol, ethylene glycol and ethanol were detected, but remained within limits authorized for food and pharmaceutical products. Terpenic compounds and aldehydes were found in the products, in particular formaldehyde and acrolein. No sample contained nitrosamines at levels above the limit of detection (1 μg/g). Residual solvents such as 1,3-butadiene, cyclohexane and acetone, to name a few, were found in some products. None of the products under scrutiny were totally exempt of potentially toxic compounds. However, for products other than nicotine, the oral acute toxicity of the e-liquids tested seems to be of minor concern. However, a minority of liquids, especially those with flavorings, showed particularly high ranges of chemicals, causing concerns about their potential toxicity in case of chronic oral exposure
Acetaldehyde · Acetone · Acrolein · Diethylene glycol · Ethanol · Ethylene glycol · Preservative · Toxicity · Chemistry · Indoor Air Quality and Microbial Exposure · Respiratory and Cough-Related Research · Smoking Behavior and Cessation · Organic Chemistry
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| Unique citing works | 7 |
|---|---|
| Citations per year | 1 |
| Citation span | 2019 - 2025 (7) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 7 |