Outcomes of Covid-19 Patients Admitted to the Intermediate Respiratory Care Unit

Non-Invasive Respiratory Therapy in a Sequential Protocol

Bibliographic Data

ID15495463
AuthorsMercè Gasa (0000-0002-4702-0768, Bellvitge University Hospital, corresponding author), Yolanda Ruíz (0000-0002-1395-7157, Bellvitge University Hospital), Ana Córdoba-Izquierdo (Bellvitge University Hospital), Mikel Sarasate (0000-0003-2730-7160, Bellvitge University Hospital), Ester Cuevas (0000-0002-7999-994X, Bellvitge University Hospital), Guillermo Suárez-Cuartín (0000-0003-2320-6047, Bellvitge University Hospital), Lidia Méndez (0000-0002-8129-9539, Bellvitge University Hospital), Julio-César Alfaro-Álvarez (0000-0001-6120-6430, Hospital de Viladecans), Joan Sabater‐Riera (0000-0003-1246-5537, Bellvitge University Hospital), Joan Sabater-Riera (Bellvitge University Hospital), Xosé Pérez-Fernández (0000-0002-5903-6927, Bellvitge University Hospital), María Molina‐Molina (0000-0002-1852-1723, Bellvitge University Hospital), María Molina-Molina (Bellvitge University Hospital), Salud Santos (0000-0002-5835-1028, Bellvitge University Hospital, corresponding author)
Year2022
Volume19
Issue17
Pages10772-10772
Publication date2022-08-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph191710772
PMID36078488
OpenAlexW4293771545
LanguageEN
References cited30

The intermediate respiratory care units (IRCUs) have a pivotal role managing escalation and de-escalation between the general wards and the intensive care units (ICUs). Since the COVID-19 pandemic began, the early detection of patients that could improve on non-invasive respiratory therapies (NRTs) in IRCUs without invasive approaches is crucial to ensure proper medical management and optimize limiting ICU resources. The aim of this study was to assess factors associated with survival, ICU admission and intubation likelihood in COVID-19 patients admitted to IRCUs. Observational retrospective study in consecutive patients admitted to the IRCU of a tertiary hospital from March 2020 to April 2021. Inclusion criteria: hypoxemic respiratory failure (SpO 2 ≤ 94% and/or respiratory rate ≥ 25 rpm with FiO 2 > 50% supplementary oxygen) due to acute COVID-19 infection. Demographic, comorbidities, clinical and analytical data, and medical and NRT data were collected at IRCU admission. Multivariate logistic regression models assessed factors associated with survival, ICU admission, and intubation. From 679 patients, 79 patients (12%) had an order to not do intubation. From the remaining 600 (88%), 81% survived, 41% needed ICU admission and 37% required intubation. In the IRCU, 51% required non-invasive ventilation (NIV group) and 49% did not (non-NIV group). Older age and lack of corticosteroid treatment were associated with higher mortality and intubation risk in the scheme, which could be more beneficial in severe forms. Initial NIV does not always mean worse outcomes

Anesthesia · Intensive care · Intensive care medicine · Intensive care unit · Intubation · Logistic regression · Mechanical ventilation · Oxygen therapy · Respiratory care · Respiratory failure · Retrospective cohort study · Intensive Care Unit Cognitive Disorders · Long-Term Effects of COVID-19 · Medicine · Respiratory Support and Mechanisms · Emergency Medicine · Internal Medicine

Tools

Open DOIOpen Access