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Evaluation of the Use of Sterilized and Non-Sterilized Peruibe Black Mud in Patients with Knee Osteoarthritis

Bibliographic Data

ID15496166
AuthorsPaulo Fávio Macedo Gouvêa (Instituto de Pesquisas Energéticas e Nucleares), Zélia Maria Nogueira Britschka (Instituto de Pesquisas Energéticas e Nucleares), Cristina de Oliveira Massoco Salles Gomes (Universidade de São Paulo), Nicolle Queiroz‐Hazarbassanov (0000-0002-5692-0565, Universidade de São Paulo), Nicolle Gilda Teixeira de Queiroz (Universidade de São Paulo), Pablo Antonio Vasquez Salvador (0000-0003-4168-1626, Instituto de Pesquisas Energéticas e Nucleares), Paulo Sergio Cardoso Da Silva (0000-0002-7271-2782, corresponding author), Paulo Sergio Cardoso Silva (0000-0002-9351-9201, Instituto de Pesquisas Energéticas e Nucleares, corresponding author)
Year2021
Volume18
Issue4
Pages1666-1666
Publication date2021-02-09
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18041666
PMID33572416
OpenAlexW3126816134
LanguageEN
Citations received1
References cited32

This study aimed to evaluate the effects of treatment with Peruíbe Black Mud (PBM) on the clinical parameters and quality of life of patients with knee osteoarthritis and to compare the effects of PBM samples simply matured in seawater and PBM sterilized by gamma radiation. A controlled, double-blind trial was conducted with 41 patients divided into two treatment groups composed of 20 and 21 patients: one group was treated with matured PBM and the other with sterilized PBM. Evaluations were done using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Medical Outcomes Study Short Form 36 (SF-36) questionnaires, the Kellgren and Lawrence (KL) radiographic scale, and the quantification of the serum levels of inflammatory biomarkers. An improvement in pain, physical functions, and quality of life was observed in all of the patients who underwent treatment with both simply matured and sterilized PBM. Nine patients showed remission in the KL radiographic scale, but no statistically significant differences were observed in the serum levels of inflammatory mediators before or after treatment. Peruíbe Black Mud proves to be a useful tool as an adjuvant treatment for knee osteoarthritis (OA), as shown by the results of the WOMAC and SF-36 questionnaires and by the remission of the radiographic grade of some patients on the Kellgren and Lawrence scale

Alternative medicine · Clinical trial · Osteoarthritis · Pathology · Physical therapy · Quality of life (healthcare · WOMAC · Complementary and Alternative Medicine Studies · Health, psychology, and well-being · Medicine · Therapeutic Uses of Natural Elements · Internal Medicine · Surgery

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Unique citing works1
Citations per year0,2
Citation span2021 - 2021 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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