Impaired Glucose Metabolism in Bipolar Patients
The Role of Psychiatrists in Its Detection and Management
Bibliographic Data
| ID | 15499114 |
|---|---|
| Authors | Dorota Łojko (0000-0002-5800-3963, Poznan University of Medical Sciences, corresponding author), Maciej Owecki (0000-0002-9060-0274, Poznan University of Medical Sciences), Aleksandra Suwalska (0000-0002-5759-5151, Poznan University of Medical Sciences) |
| Year | 2019 |
| Volume | 16 |
| Issue | 7 |
| Pages | 1132-1132 |
| Publication date | 2019-03-29 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph16071132 |
| PMID | 30934836 |
| OpenAlex | W2925062142 |
| Language | EN |
| Citations received | 2 |
| References cited | 60 |
Bipolar patients have a higher risk of type 2 diabetes and obesity, which are associated with cardiovascular diseases as the leading cause of death in this group. Additionally, there is growing evidence that impaired glucose metabolism in bipolar patients is associated with rapid cycling, poor response to mood stabilizers and chronic course of illness. The aim of the study was to assess the prevalence of type 2 diabetes and other types of impaired glucose metabolism in bipolar patients along with an evaluation of the Fasting Triglycerides and Glucose Index (TyG) as a method of the insulin sensitivity assessment. The analysis of fasting glycemia, insulinemia and lipid profile in euthymic bipolar patients was performed, and the Homeostasis model assessment for insulin resistance (HOMA-IR) and TyG were computed. Type 2 diabetes was observed in 9% and insulin resistance with HOMA-IR in 48% of patients. The TyG and HOMA-IR indices were correlated ( p < 0.0001), the TyG index value of 4.7 had the highest sensitivity and specificity for insulin resistance detection. The usefulness of TyG in the recognition of insulin resistance in bipolar patients was suggested. The significant role of psychiatrists in the detection and management of impaired glucose metabolism in bipolar patients was presented
Bipolar disorder · Carbohydrate Metabolism · Diabetes mellitus · Impaired glucose tolerance · Insulin · Insulin resistance · Lipid metabolism · Obesity · Type 2 diabetes · Bipolar Disorder and Treatment · Diabetes Treatment and Management · Electrolyte and hormonal disorders · Medicine · Endocrinology · Internal Medicine
Classification and Diagnosis of Diabetes
Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome
Homeostasis model assessment
Canadian Network for Mood and Anxiety Treatments ( Canmat ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder
A Rating Scale for Mania
Development of a Rating Scale for Primary Depressive Illness
Factors Associated with the Risk of Developing Coronary Artery Disease in Medicated Patients with Major Depressive Disorder
| Unique citing works | 2 |
|---|---|
| Citations per year | 0,4 |
| Citation span | 2021 - 2022 (2) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 2 |