Vitamin D Levels in Children with Recurrent Acute Tonsillitis in Jordan
A Case-Control Study
Bibliographic Data
| ID | 15499132 |
|---|---|
| Authors | Baeth Al‐Rawashdeh (0000-0003-2648-0180, University of Jordan, corresponding author), Mohammad Altawil (South Infirmary Victoria University Hospital), Fareed Ahmad (0000-0002-6359-6601, University of Jordan), Abdelrahman Alharazneh (Mutah University), Lubna Hamdan (Vanderbilt University Medical Center), Ahmed S H Muamar (University of Jordan), Sireen M Alkhaldi (0000-0002-7584-4502, University of Jordan), Zahraa Al-Tamimi, Zahraa Tamimi (University of Jordan), Rawand Husami (University of Jordan), Raihan Husami (University of Jordan), Nidaa A Ababneh (0000-0002-2155-3013, University of Jordan) |
| Year | 2022 |
| Volume | 19 |
| Issue | 14 |
| Pages | 8744-8744 |
| Publication date | 2022-07-18 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph19148744 |
| PMID | 35886596 |
| OpenAlex | W4285729522 |
| Language | EN |
| References cited | 24 |
Background: Vitamin D is essential for many functions of the body. In addition to its primary function of regulating the absorption of calcium in the small intestine, its role in the immune system has recently been studied. The current study aimed to test the impact of vitamin D deficiency on the rate of recurrent acute tonsillitis in children. Methods: According to Paradise criteria, two hundred forty-two children with recurrent acute tonsillitis were recruited. A group of healthy children (n = 262) was also recruited as controls. Poisson regression was run to predict the number of tonsillitis episodes per year based on vitamin D levels. The mean vitamin D level in the study group was lower than in the control group (p < 0.0001). Poisson regression of the rate of recurrent tonsillitis and vitamin D level (OR = 0.969 (95% CI, 0.962−0.975)) showed that for every single unit increase in vitamin D level, there was a 3.1% decrease in the number of tonsillitis episodes per year (p < 0.0001). Conclusions: Vitamin D deficiency is associated with higher rates of recurrent acute tonsillitis. Future controlled trials should investigate the role of vitamin D supplementation in reducing the rate of recurrent tonsillitis
Acute Tonsillitis · Poisson regression · Population · Tonsillitis · Vitamin · Vitamin D and neurology · Autoimmune and Inflammatory Disorders Research · Dermatological and COVID-19 studies · Medicine · Vitamin D Research Studies · Gastroenterology · Internal Medicine · Pediatrics
| Highly cited | No |
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