Cardiovascular Autonomic Control, Sleep and Health Related Quality of Life in Systemic Sclerosis
Bibliographic Data
| ID | 15499705 |
|---|---|
| Authors | Angelica Carandina (0000-0002-7170-4852, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Chiara Bellocchi (0000-0001-8326-7904, University of Milan), Gabriel Dias Rodrigues (0000-0002-9258-2954, Universidade Federal Fluminense), Lorenzo Beretta (0000-0002-6529-6258, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Nicola Montano (0000-0001-9206-0075, University of Milan), Eleonora Tobaldini (0000-0003-3627-8293, University of Milan, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 5 |
| Pages | 2276-2276 |
| Publication date | 2021-02-25 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18052276 |
| PMID | 33668942 |
| OpenAlex | W3129914991 |
| Language | EN |
| References cited | 41 |
Chronic pain and dysautonomic symptoms deteriorate Systemic sclerosis (SSc) patients' health-related quality of life with serious repercussions on social life and even on sleep. Heart Rate Variability (HRV) analysis can identify cardiovascular autonomic control impairment in subclinical condition. The aim of the present observational cross-sectional study was to assess the relationship between dysautonomic symptoms, quality of life status and cardiovascular autonomic profile. ECG and respiration were recorded at rest in 20 SSc patients. HRV analysis was performed using two different approaches: Linear spectral analysis and non-linear symbolic analysis. Pain was evaluated using the Numeric Rating Scale (NRS) and 3 questionnaires were administered for the evaluation of sleep quality (PSQI), mood tone (PHQ-9) and disability (HAQ). We found that sleep impairment was related to sympathetic predominance at rest measured as low-frequency/high-frequency ratio (LF/HF) (r = 0.48 and p = 0.033); poorer sleep quality was related to higher pain values (r = 0.48 and p = 0.034) and depressive symptoms (r = 0.82 and p p = 0.038 & r = 0.55 and p = 0.012, respectively). In conclusion dysautonomia and chronic pain showed a severe impact on sleep quality and disability with a consequent worsening of depressive symptom in our cohort of SSc patients
Blood pressure · Cardiology · Cohort · Disease · Dysautonomia · Fibromyalgia · Heart rate · Heart rate variability · Mood · Physical therapy · Psychiatry · Quality of life (healthcare · Sleep (system call · Subclinical infection · Fibromyalgia and Chronic Fatigue Syndrome Research · Heart Rate Variability and Autonomic Control · Medicine · Systemic Sclerosis and Related Diseases · Internal Medicine
| Highly cited | No |
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