Effectiveness of Paliperidone Palmitate in Reducing Acute Psychiatric Service Use for Patients Suffering from Psychosis—A Retrospective Mirror-Image Study
Bibliographic Data
| ID | 15500125 |
|---|---|
| Authors | Chun Ting Chan (Duke-NUS Medical School, corresponding author), Swapna Verma (0000-0003-1098-0842, Duke-NUS Medical School), Mythily Subramaniam (0000-0003-4530-1096, Institute of Mental Health), Edimansyah Abdin (0000-0002-1016-3298, Institute of Mental Health), Jenny Tay (Institute of Mental Health) |
| Year | 2023 |
| Volume | 20 |
| Issue | 4 |
| Pages | 3403-3403 |
| Publication date | 2023-02-15 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph20043403 |
| PMID | 36834095 |
| OpenAlex | W4320919774 |
| Language | EN |
| References cited | 27 |
Poor adherence to antipsychotic treatment is a leading cause of relapse for patients suffering from psychotic disorders and the use of long-acting injectable antipsychotics (LAI) may lead to improved clinical outcomes. This was a 1-year mirror-image study examining the clinical outcomes after monthly administration of paliperidone palmitate (PP1M). The primary outcome measure was the total days of psychiatric hospitalization in the 1-year before and 1-year after initiation of PP1M. Data from 158 patients were included in the study. Most of the patients suffered from schizophrenia. In the year after initiation of PP1M, the mean number of hospitalization days fell from 106.53 to 19.10 ( p < 0.001). There were significant reductions in the mean number of hospitalizations and emergency room visits. The use of paliperidone palmitate is associated with significant reduction in both the number of admissions and days of psychiatric hospitalization
Antipsychotic · Paliperidone · Paliperidone Palmitate · Psychiatry · Psychosis · Retrospective cohort study · Schizophrenia (object-oriented programming · Medicine · Mental Health and Psychiatry · Parkinson's Disease Mechanisms and Treatments · Schizophrenia research and treatment · Emergency Medicine · Internal Medicine
| Highly cited | No |
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