The Association between Blood Pressure Trajectories and Risk of Cardiovascular Diseases among Non-Hypertensive Chinese Population
A Population-Based Cohort Study
Bibliographic Data
| ID | 15501992 |
|---|---|
| Authors | Fang Li (0000-0001-9180-3615, Central South University), Qian Lin (0009-0001-4001-5229, Central South University), Mingshu Li (0000-0002-5129-6097, Central South University), Lizhang Chen (0000-0001-5426-0519, Central South University, corresponding author), Yingjun Li (0000-0002-8339-2104, Hangzhou Medical College, corresponding author) |
| Year | 2021 |
| Volume | 18 |
| Issue | 6 |
| Pages | 2909-2909 |
| Publication date | 2021-03-12 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18062909 |
| PMID | 33809125 |
| OpenAlex | W3136958072 |
| Language | EN |
| References cited | 49 |
Although previous studies have discussed the association between trajectories of blood pressure (BP) and risk of cardiovascular diseases (CVDs), the association among the non-hypertensive general population of youth and middle age has not been elucidated. We used the growth mixture model to explore the trajectories of BP among the non-hypertensive Chinese population and applied Cox regression to evaluate the association between trajectories of BP and the risk of stroke or myocardial infarction (MI). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were categorized into three classes, respectively. Statistically significant associations were observed between SBP trajectories and stroke (range of adjusted hazard ratios (aHR): 1.369-3.837) or MI (rang of aHR = 6.047-13.017). Association between DBP trajectories and stroke (aHR: 3.685) or MI (range of aHR = 1.312-2.821) were also observed, although they did not reach statistical significance. Trajectories of SBP were more important risk factors than that of DBP in stroke and MI in our study population. BP management is important among pre-hypertensive adults to prevent stroke and MI when they age. Well-designed research with a larger sample size is required to confirm our findings and develop efficient methods to prevent CVDs
Blood pressure · Cardiology · Cohort · Confidence interval · Environmental health · Hazard ratio · Myocardial infarction · Population · Proportional hazards model · Stroke (engine · Blood Pressure and Hypertension Studies · Cardiovascular Health and Disease Prevention · Medicine · Sodium Intake and Health · Internal Medicine
Multiple Imputation for Missing Data
Status of Hypertension in China
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure The JNC 7 Report
Mortality, morbidity, and risk factors in China and its provinces, 1990–2017
Global, regional, and national burden of stroke, 1990–2016
Performance of Factor Mixture Models as a Function of Model Size, Covariate Effects, and Class-Specific Parameters
Maximum Likelihood from Incomplete Data Via the EM Algorithm
Testing the number of components in a normal mixture
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019
Growth Mixture Modeling of Adolescent Body Mass Index Development
| Citation velocity | historical |
|---|---|
| Highly cited | No |