Endocrine Disruptors and Obesity

An Examination of Selected Persistent Organic Pollutants in the NHANES 1999–2002 Data

Bibliographic Data

ID15505366
AuthorsMai Elobeid (University of Alabama at Birmingham), Mai A Elobeid (Department of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL, 35294, USA), David W Padilla (Old Dominion University), David Brock (0000-0003-4006-5610, University of Alabama at Birmingham), David B Brock (Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA), Miguel A Ruden (Wayne State University), David B Allison (0000-0003-3566-9399, University of Alabama at Birmingham, corresponding author)
Year2010
Volume7
Issue7
Pages2988-3005
Publication date2010-07-23
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph7072988
PMID20717554
OpenAlexW2105763225
LanguageEN
Citations received10
References cited30

Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999-2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p' DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with higher WC and BMI, whereas, ln trans-nonachlor decreased with higher BMI. Hence, BMI and WC are associated with POPs levels, making the chemicals plausible contributors to the obesity epidemic

Body mass index · Endocrine system · Environmental health · Hormone · National Health and Nutrition Examination Survey · Obesity · Pollutant · Waist · Chemistry · Effects and risks of endocrine disrupting chemicals · Medicine · Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Endocrinology

Tools

Open DOISci-HubOpen Access