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Impact of Prescribed Exercise on the Physical and Cognitive Health of Adults with Down Syndrome

The MinDSets Study

Bibliographic Data

ID15508561
AuthorsViviane Merzbach (0000-0002-2739-9176, Anglia Ruskin University), Michael N Ferrandino (0000-0002-5097-0318, Anglia Ruskin University), Michael Ferrandino (Anglia Ruskin University), Marie Gernigon (0000-0002-0303-7293, Université d'Orléans), Jorge Marques Pinto (0000-0002-6118-3694, Anglia Ruskin University), Adrian Scruton (Anglia Ruskin University), Dan Gordon (0000-0002-3161-8984, Université Paris-Saclay, corresponding author)
Year2023
Volume20
Issue23
Pages7121-7121
Publication date2023-11-29
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph20237121
PMID38063551
OpenAlexW4389201401
LanguageEN
Citations received1
References cited41

The duplication of chromosome 21, as evidenced in Down Syndrome (DS), has been linked to contraindications to health, such as chronotropic and respiratory incompetence, neuromuscular conditions, and impaired cognitive functioning. The purpose of this study was to examine the effects of eight weeks of prescribed exercise and/or cognitive training on the physical and cognitive health of adults with DS. Eighty-three participants (age 27.1 ± 8.0 years) across five continents participated. Physical fitness was assessed using a modified version of the six-minute walk test (6MWT), while cognitive and executive functions were assessed using the Corsi block test, the Sustained-Attention-To-Response Task (SART), and the Stroop task (STROOP). All were completed pre- and post-intervention. Participants were assigned to eight weeks of either exercise (EXE), 3 × 30 min of walking/jogging per week, cognitive training (COG) 6 × ~20 min per week, a combined group (COM), and a control group (CON) engaging in no intervention. 6MWT distance increased by 11.4% for EXE and 9.9% for COM ( p p p < 0.05). Walking generated a cognitive load attributed to heightened levels of vigilance and decision-making, suggesting that exercise should be adopted within the DS community to promote physical and cognitive well-being

Cognition · Executive functions · Physical medicine and rehabilitation · Physical therapy · Psychiatry · Stroop effect · Diabetes Management and Research · Down syndrome and intellectual disability research · Medicine · Psychology

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Citations per year0.5
Citation span2024 - 2024 (1)
Highly citedNo

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