Exercise and Reduced Nicotine Content Cigarettes in Adult Female Smokers
A Pilot Trial
Bibliographic Data
| ID | 15512641 |
|---|---|
| Authors | Chaofan Li (0000-0001-6238-1257, Shandong University), Nengliang Yao (0000-0001-9000-0378, Shandong University), Stephanie L Miller (University of Virginia), Christopher Macpherson (University of Virginia), Taryn E Hassinger (0000-0003-3015-4126, University of Virginia), Taryn Hassinger (University of Virginia), Kaitlin M Love (0000-0002-9352-393X, University of Virginia), Steven K Malin (0000-0002-7360-6711, Rutgers, the State University of New Jersey, corresponding author) |
| Year | 2022 |
| Volume | 19 |
| Issue | 11 |
| Pages | 6647-6647 |
| Publication date | 2022-05-29 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph19116647 |
| PMID | 35682232 |
| OpenAlex | W4281771650 |
| Language | EN |
| Citations received | 1 |
| References cited | 25 |
Background: Although Reduced Nicotine Cigarettes (RNC) are suggested to improve smoking cessation and cardiometabolic health in relation to cancer risk, the effectiveness of exercise training with RNC on smoking cessation and cardiometabolic health is unknown. Methods: Female smokers (N = 27) were randomized to: (1) usual nicotine cigarettes (i.e., control), (2) RNC or (3) RNC plus exercise treatment for 12 weeks. Smoking withdrawal symptoms (e.g., Wisconsin Smoking Withdrawal Scale) and cardiometabolic health (e.g., weight, VO2max, resting respiratory exchange ratio (RER), glucose, HOMA-IR) were examined before and after treatment. Results: Treatments had no differential effect on weight (p = 0.80; partial η2 = 0.29), VO2max (p = 0.20, partial η2 = 0.18), or total cholesterol/HDL ratios (p = 0.59, partial η2 = 0.06). However, RNC + Exercise tended to maintain RER (i.e., fat oxidation; p = 0.10, partial η2 = 0.10) as well as insulin resistance (p = 0.13, partial η2 = 0.25) and cortisol compared (p = 0.06, partial η2 = 0.30) with control and RNC. Increased VO2max was also associated with lower nicotine dependence scores (r = −0.50, p < 0.05). Conclusion: In this pilot study, improved fitness was associated with lower nicotine dependence. Additional work is warranted to examine the effects of exercise in smokers as a tool to improving smoking cessation and lower disease risk
Blood pressure · Heart rate · Nicotine · Physical therapy · Randomized controlled trial · Respiratory exchange ratio · Smoking cessation · Varenicline · VO2 max · Health and Lifestyle Studies · Medicine · Obesity, Physical Activity, Diet · Smoking Behavior and Cessation · Internal Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |