Long-Term Survival of Older Patients Hospitalized for Covid-19. Do Clinical Characteristics upon Admission Matter

Bibliographic Data

ID15513293
AuthorsMichał Chojnicki (0000-0003-3301-0662, Poznan University of Medical Sciences), Agnieszka Neumann‐Podczaska (0000-0002-0060-7430, Poznan University of Medical Sciences), Mikołaj Seostianin (0000-0002-7754-3949, Poznan University of Medical Sciences, corresponding author), Zofia Tomczak (0000-0003-2508-0580, Poznan University of Medical Sciences), Hamza Tariq (0000-0002-4576-7323, Poznan University of Medical Sciences), Jerzy Chudek (0000-0002-6367-7794, Medical University of Silesia), ławomir Tobi (0000-0002-0764-3258, Poznan University of Medical Sciences), Iwona Mozer‐Lisewska (Poznan University of Medical Sciences), Aleksandra Suwalska (0000-0002-5759-5151, Poznan University of Medical Sciences), Andrzej Tykarski (0000-0001-9786-6334, Poznan University of Medical Sciences), Piotr Merks (0000-0001-8966-3799, Cardinal Stefan Wyszynski University in Warsaw), Sylwia Kropińska (0000-0003-0518-5852, Poznan University of Medical Sciences), Małgorzata Sobieszczańska (0000-0003-4374-9866, Wroclaw Medical University), Frank Romanelli (0000-0002-3792-7390, University of Kentucky), Katarzyna Wieczorowska–Tobi (0000-0003-4017-3013, Poznan University of Medical Sciences)
Year2021
Volume18
Issue20
Pages10671-10671
Publication date2021-10-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph182010671
PMID34682421
OpenAlexW3206990928
LanguageEN
References cited10

Older adults are particularly susceptible to COVID-19 in terms of both disease severity and risk of death. To compare clinical differences between older COVID-19 hospitalized survivors and non-survivors, we investigated variables influencing mortality in all older adults with COVID-19 hospitalized in Poznań, Poland, through the end of June 2020 ( n = 322). In-hospital, post-discharge, and overall 180-day mortality were analyzed. Functional capacity prior to COVID-19 diagnosis was also documented. The mean age of subjects was 77.5 ± 10.0 years; among them, 191 were females. Ninety-five (29.5%) died during their hospitalization and an additional 30 (9.3%) during the post-discharge period (up to 180 days from the hospital admission). In our study, male sex, severe cognitive impairment, underlying heart disease, anemia, and elevated plasma levels of IL-6 were independently associated with greater mortality during hospitalization. During the overall 180-day observation period (from the hospital admission), similar characteristics, excluding male sex and additionally functional impairment, were associated with increased mortality. During the post-discharge period, severe functional impairment remained the only determinant. Therefore, functional capacity prior to diagnosis should be considered when formulating comprehensive prognoses as well as care plans for older patients infected with SARS-CoV-2

Anemia · Cognitive impairment · Coronavirus disease 2019 (COVID-19 · Disease · Functional impairment · Hospital admission · Hospital discharge · Infectious disease (medical specialty · COVID-19 and healthcare impacts · COVID-19 Clinical Research Studies · Long-Term Effects of COVID-19 · Medicine · Emergency Medicine · Internal Medicine · Pediatrics