Can Active Aerobic Exercise Reduce the Risk of Cardiovascular Disease in Prehypertensive Elderly Women by Improving HDL Cholesterol and Inflammatory Markers
Bibliographic Data
| ID | 15513786 |
|---|---|
| Authors | Nayoung Ahn (0000-0002-7300-5174, Keimyung University), Kijin Kim (0000-0002-2067-3240, Keimyung University, corresponding author) |
| Year | 2020 |
| Volume | 17 |
| Issue | 16 |
| Pages | 5910-5910 |
| Publication date | 2020-08-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17165910 |
| PMID | 32824020 |
| OpenAlex | W3049525468 |
| Language | EN |
| Citations received | 4 |
| References cited | 69 |
This study aims to verify the efficacy of exercise programs designed to prevent and treat hypertension-induced cardiovascular disease (CVD) by analyzing the effects of a 6-month active aerobic exercise program, administered to prehypertensive elderly women, on reducing the risk of developing CVD by enhancing their physical fitness level and improving the detailed markers of high-density lipoprotein cholesterol (HDL-C) and inflammatory markers. We assigned the elderly women (≥65 years) recruited into normal blood pressure (120-129/80-84; NBP, n = 18) and high-normal blood pressure (130-139/85-89; HNBP, n = 12) groups according to the European guidelines for the management of arterial hypertension. The exercise program was made up of combined workouts of elastic band resistance exercise and aerobics with dance music. The program took place three times a week for six months, with each session lasting 60 min. We measured pre- and post-intervention body composition, blood pressure, physical fitness level, blood lipids profile, HDL-C, SAA, TNF-α, IL-6, IL-4, IL-15, CRP, and HSP70 and calculated the Framingham risk scores for comparison. A significant post-intervention reduction in the mean systolic blood pressure (SBP) was observed in the HNBP group ( p p p p p p p p p < 0.01). In conclusion, the 6-month active aerobic exercise program of moderate intensity administered to prehypertensive elderly women (≥65 years) had the effect of reducing the 10-year CVD risk through a substantial reduction in SBP, overall physical fitness improvement, increase in HDL-C, decrease in SAA concentration, and substantial decrease in inflammatory biomarkers. It was also confirmed that an increase in anti-inflammatory markers, which showed a small range of increase with respect to the decrease in blood pressure, may have a major effect
Aerobic exercise · Blood lipids · Blood pressure · Cholesterol · Disease · Framingham Risk Score · Physical fitness · Physical therapy · Prehypertension · Cardiovascular and exercise physiology · Exercise and Physiological Responses · Medicine · Physical Activity and Health · Internal Medicine
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| Citations per year | 0.8 |
|---|---|
| Citation span | 2021 - 2025 (5) |
| Highly cited | No |