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Lipoprotein Profile in Populations from Regions of the Russian Federation

Esse-RF Study

Bibliographic Data

ID15513787
AuthorsV A Metelskaya (0000-0001-8665-9129, National Research Center for Preventive Medicine, corresponding author), А Shalnova (0000-0003-2087-6483, National Research Center for Preventive Medicine), Е B Yarovaya (0000-0002-6615-4315, Lomonosov Moscow State University), В А Куценко (0000-0001-9844-3122, Lomonosov Moscow State University), S А Boytsov (0000-0001-6998-8406, National Medical Research Center of Cardiology), Е V Shlyakhto (0000-0003-2929-0980, Federal Almazov North-West Medical Research Centre), Oxana M Drapkina (0000-0002-4453-8430), Oxana Drapkina (0000-0003-0323-2635, National Research Center for Preventive Medicine)
Year2022
Volume19
Issue2
Pages931-931
Publication date2022-01-14
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19020931
PMID35055754
OpenAlexW4206187679
LanguageEN
References cited4

This study aimed to describe the dyslipidemia prevalence and pattern among adult populations from different regions ( n = 13) of the Russian Federation (RF). Randomly selected samples ( n = 22,258, aged 25-64) were studied according to the ESSE-RF protocol. Lipoprotein parameters were estimated by routine methods. Statistical analyses were performed using R software (v.3.5.1). The overall dyslipidemia prevalence was 76.1% (76.9/75.3% for men/women). In women, total cholesterol (TC) and low-density lipoprotein (LDL)-C levels gradually increased with age (from 4.72 to 5.93 and from 2.76 to 3.79 mmol/L, respectively); in men, they reached a maximum by 45-54 (5.55 and 3.55 mmol/L, respectively) and then decreased. No differences in high-density lipoprotein (HDL)-C in men of different ages were found, but slight decreases in HDL-C and apo AI were observed in women by 55-64 years. No pronounced associations between education and lipid levels in men were observed; higher-educated women showed significantly better lipoprotein profiles. Similar associations between lipids and income level were detected. Women from rural areas had higher TC and triglycerides than urban residents. Regardless of sex, rural residents had higher HDL-C and apo AI, and reduced apo B/apo AI. Conclusion: Information on the peculiarities of dyslipidemia prevalence and lipoprotein profile depending on sex, age, residential place, and socioeconomic status is useful for assessing the global ASCVD risk, and for risk modeling based on national data

Apolipoprotein B · Cholesterol · Disease · Dyslipidemia · Environmental health · High-density lipoprotein · Lipoprotein · Population · Socioeconomic status · Cardiovascular Health and Risk Factors · Demography · Healthcare Systems and Public Health · Lipoproteins and Cardiovascular Health · Medicine · Endocrinology · Gerontology · Internal Medicine

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