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Association between Residential Distance from Home to Hospital and Amputation of a Lower Extremity among Peripheral Artery Disease Patients in Japan

Bibliographic Data

ID15514285
AuthorsNobuko Hayashi (0000-0003-3051-139X, Tokyo Medical and Dental University), Yusuke Matsuyama (0000-0002-6114-5604, Tokyo Medical and Dental University), Takashi Fujiwara (0000-0002-1074-3954, Tokyo Medical and Dental University, corresponding author)
Year2022
Volume19
Issue20
Pages13088-13088
Publication date2022-10-12
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph192013088
PMID36293667
OpenAlexW4304689270
LanguageEN
References cited22

Lack of access to care can lead to poor outcomes for patients with peripheral artery disease (PAD). We investigated the association between residential distance from home to hospital and amputation of the lower extremity among PAD patients in the Chiba peninsula, Japan. A retrospective cohort study with an average follow-up period of 2.96 years was conducted using data from 630 PAD patients who visited two hospitals in the Chiba peninsula, Japan, between 1 April 2010 to 31 March 2020. Information on disease status, residential address, and covariates was obtained from medical records. The association between amputation of a lower extremity, including toe amputation, and residential distance was evaluated by Cox proportional hazards model. Age, gender, Fontaine class, endovascular treatment, dialysis, diabetes mellitus, hypertension, dyslipidemia, current or past smoking, and aspirin use were adjusted. The median residential distance was 18.9 km (interquartile range, IQR: 22.1). Ninety-two patients (14.6%) underwent amputation of the lower extremity during the follow-up period. The longer residential distance was significantly associated with a higher risk of lower extremity amputation (hazard ratio per IQR = 1.35, 95% confidence interval, 1.01-1.82) after adjusting for covariates. Poorer access to a hospital, assessed as a longer residential distance from home to a hospital, was associated with amputation of the lower extremity among PAD patients

Amputation · Arterial disease · Confidence interval · Diabetes mellitus · Dialysis · Hazard ratio · Interquartile range · Physical therapy · Proportional hazards model · Retrospective cohort study · Vascular disease · Diabetic Foot Ulcer Assessment and Management · Diagnosis and Treatment of Venous Diseases · Medicine · Peripheral Artery Disease Management · Emergency Medicine · Internal Medicine · Surgery

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